NCT01116453

Brief Summary

Since there is unsatisfactory effect by currently pharmacologic therapies and preventive strategies for dysmenorrhea, this study is designed to evaluate the efficacy and quality of life of acupuncture for patients with dysmenorrhea based on the theory of traditional Chinese Medicine.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
22

participants targeted

Target at below P25 for phase_3

Timeline
Completed

Started May 2010

Typical duration for phase_3

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2010

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

May 3, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 5, 2010

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2012

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2012

Completed
Last Updated

March 7, 2013

Status Verified

February 1, 2013

Enrollment Period

2.3 years

First QC Date

May 3, 2010

Last Update Submit

March 5, 2013

Conditions

Keywords

dysmenorrheaacupuncturerandomized controlled trial

Outcome Measures

Primary Outcomes (1)

  • visual analogue scale of pain

    every 2 months

Secondary Outcomes (7)

  • score of questionnaire of quality of life (SF-36)

    every 2 months

  • amount of additional medication

    every 2 months

  • degree of restriction of daily life activities

    every 2 months

  • degree of absence from work or school

    every 2 months

  • overall improvement in dysmenorrhea

    end of acupuncture treatment

  • +2 more secondary outcomes

Study Arms (2)

Acupuncture

EXPERIMENTAL
Procedure: acupuncture

Usual Care

ACTIVE COMPARATOR

usual care followed by delayed acupuncture

Procedure: usual care

Interventions

acupuncturePROCEDURE

acupuncture on the acupoints of ST44 and ST43 of bilateral feet for 2 months, then followed-up for another 2months

Also known as: body acupuncture
Acupuncture
usual carePROCEDURE

usual care with medication and behavior therapy for 2 months, followed by acupuncture for additional 2 months

Also known as: delayed acupuncture
Usual Care

Eligibility Criteria

Age13 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • non-pregnant women who are at least 13 years old
  • the one who meet any one of the following two criteria: 1.suffering from dysmenorrhea in recent 3 menstrual periods; 2.dysmenorrhea with poor response to non-steroid anti-inflammation drugs

You may not qualify if:

  • intrauterine device-related dysmenorrhea
  • history of alcohol or drug abuser
  • women who are pregnant, as determined by a urine pregnancy test
  • history of adverse reaction to acupuncture
  • received herb or acupuncture therapy within one month prior to enrollment
  • poor compliance to investigator's advice

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University Hospital Yun-Lin Branch

Douliu, 640, Taiwan

Location

Related Publications (1)

  • Witt CM, Reinhold T, Brinkhaus B, Roll S, Jena S, Willich SN. Acupuncture in patients with dysmenorrhea: a randomized study on clinical effectiveness and cost-effectiveness in usual care. Am J Obstet Gynecol. 2008 Feb;198(2):166.e1-8. doi: 10.1016/j.ajog.2007.07.041.

    PMID: 18226614BACKGROUND

MeSH Terms

Conditions

Dysmenorrhea

Interventions

Acupuncture Therapy

Condition Hierarchy (Ancestors)

Menstruation DisturbancesPathologic ProcessesPathological Conditions, Signs and SymptomsPelvic PainPainNeurologic ManifestationsSigns and Symptoms

Intervention Hierarchy (Ancestors)

Complementary TherapiesTherapeutics

Study Officials

  • Chien-Hsun Huang, MD, MSc

    National Taiwan University Hospital, Yun-Lin Branch

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 3, 2010

First Posted

May 5, 2010

Study Start

May 1, 2010

Primary Completion

August 1, 2012

Study Completion

November 1, 2012

Last Updated

March 7, 2013

Record last verified: 2013-02

Locations