Sponsor study identifier
interventional
50
1 country
1
Study Start
March 2010
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
May 2011
Actual (reported)Study Completion
May 2011
Actual (reported)A more recent prospective nonrandomized placebo-controlled double-blind clinical study demonstrated that metformin exerts a slight but significant deleterious effect on serum homocysteine (Hcy) levels in patients with PCOS, and supplementation with folate is useful to increase the beneficial effect of metformin on the vascular endothelium.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 2011
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 2010
Date type not reportedThis date has not been verified as actual or estimated.
May 3, 2010
Actual (reported)May 4, 2010
Actual (reported)May 2011
Actual (reported)May 2011
Actual (reported)Trophoblastic invasion.
Istologic evaluation of trophoblastic ivasion,
two weeks
Doppler velocimetry measurements of the uterine artery.
two weeks
metformin plus placebo
metformin plus folic acid
placebo plus folic acid
metformin 850 mg cp, 2 cps daily
metformin 850 mg cp, 2 cps daily plus folic acid 0.4 mg daily
These entries preserve how the registry describes the intervention. Their treatment roles are shown separately from molecular identities.
Grouped treatment entry
Metformin plus folic acid
The registry names several treatments. This does not confirm that participants received them together or that they form a single product.
View registry record"Pugliese" Hospital
Catanzaro, Catanzaro, 88100, Italy
Fulvio Zullo, MD
Department of Obstetrics and Gynecology, University "Magna Graecia" of Catanzaro
Stefano Palomba, MD
Department of Obstetrics and Gynecology, University "Magna Graecia" of Catanzaro
50 participants (actual enrollment reported by the registry).
First Submitted
May 3, 2010
First Posted
May 4, 2010
Study Start
March 2010
Date type not reportedThis date has not been verified as actual or estimated.
Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
Therapeutic Monitoring of Metformin in Women With Polycystic Ovary Syndrome
placebo cp, 2 cps daily
observation
Placebo 1 cp daily plus folic acid 0.4 mg daily
placebo cp, 2 cps daily
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
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Primary Completion
May 2011
Actual (reported)Study Completion
May 2011
Actual (reported)Last Updated
May 24, 2011
Record last verified: 2011-05
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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