Age-related Variability of the Efficacy and Tolerability of Alternative Pituitary Suppression Regimens in ART
1 other identifier
observational
2,000
1 country
1
Brief Summary
Age-related variability of the efficacy and tolerability of alternative pituitary suppression regimens in follicular stimulation for assisted reproduction purposes. A randomised, prospective, multi-centre clinical trial
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Apr 2010
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2010
CompletedFirst Submitted
Initial submission to the registry
April 20, 2010
CompletedFirst Posted
Study publicly available on registry
April 21, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2013
CompletedMarch 26, 2012
April 1, 2010
3 years
April 20, 2010
March 22, 2012
Conditions
Keywords
Study Arms (4)
Group A1
Age 18-34y (with short protocol)
Group A2
age 35-42y ( with short protocol)
Group B1
age 18-34y ( with long protocol)
Group B2
age 35-42y ( with long protocol)
Interventions
After down-regulation (short protocol), all patients will be stimulated with hFSH (human-derived FSH).
Eligibility Criteria
Patients addressed to follicular stimulation for in vitro fertilisation purposes will constitute the study population.
You may qualify if:
- Age 18 to 42
- First IVF attempt
- BMI 18 to 25
- Basal FSH less than 12 for subjects below the age of 35 or less than 15 for subjects aged more than 35
- Informed consent
You may not qualify if:
- Genital malformation
- Hypersensitivity to study drugs
- Major illnesses (to be specified)
- PCOS
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Shandong Universitylead
- The First Affiliated Hospital of Zhengzhou Universitycollaborator
- IBSA Institut Biochimique SAcollaborator
- The Second Hospital of Hebei Medical Universitycollaborator
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen Universitycollaborator
Study Sites (1)
Shandong University reproductive medicine researche center
Jinan, Shandong, 250000, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Zijiang Chen, Professor
Director of Shandong University reproductive medicine study center
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
April 20, 2010
First Posted
April 21, 2010
Study Start
April 1, 2010
Primary Completion
April 1, 2013
Study Completion
April 1, 2013
Last Updated
March 26, 2012
Record last verified: 2010-04