Efficacy of Transfer Factor to Prevent Upper Respiratory Tract Infections in Healthy Adults

NCT01106183 | Completed

• 1 other identifier: 38766 4Life-Transfer Factor
• Study Type: interventional
• Target: 49
• Locations: 1 country
• Sites: 1

Brief Summary

The goals of our study are to critically evaluate if a healthy population supplemented with Transfer factor experiences fewer incidences of colds and flu, or experience shorter duration of illness compared to an identical population taking placebo. In this study we will give either Transfer factor or a placebo to two groups of healthy adult men and women for a period of 7 weeks in a double-blind experimental design. The frequency and duration of colds and flu-like symptoms will be recorded during the course of the study. Saliva samples will be collected weekly and assessed for salivary IgA secretion rate. Data from this study will establish the efficacy of Transfer Factor to support a healthy immune system.

Conditions

Upper Respiratory Tract Infections Due to Influenza or Rhinovirus

Study Arms (2)

Transfer Factor

ACTIVE COMPARATOR

Transfer factor supplement; 2 capsules per day

Dietary Supplement: transfer factor

Sugar pill

PLACEBO COMPARATOR

Dietary Supplement: Placebo

Interventions

transfer factor DIETARY_SUPPLEMENT

capsules, 2 per day by mouth for 7 weeks.

Transfer Factor

Placebo DIETARY_SUPPLEMENT

cornstarch, 2 capsules per day by mouth.

Sugar pill

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Males and females (18 - 40) who are in good health

You may not qualify if:

• Subjects who are allergic to eggs (on which the supplement is based). If a volunteer is not sure if they are allergic to eggs or milk. Those who are currently smoking, have cardiovascular disease, cancer, diabetes, liver disease, renal insufficiency, any chronic disease that might interfere with study participation, BMI above 40 kg/m2, consumption of \>12 alcoholic drinks weekly, or unwillingness to stop current supplement intake. Women who are pregnant or lactating will also be excluded from the study.

Sponsors & Collaborators

• University of Utah: lead

Study Sites (1)

University of Utah

Salt Lake City, Utah, 84112, United States

Location

MeSH Terms

Interventions

Transfer Factor

Intervention Hierarchy (Ancestors)

Lymphokines; Cytokines; Intercellular Signaling Peptides and Proteins; Peptides; Amino Acids, Peptides, and Proteins; Proteins; Biological Factors

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 15, 2010
• First Posted: April 19, 2010
• Study Start: January 1, 2010
• Primary Completion: March 1, 2010
• Study Completion: March 1, 2010
• Last Updated: March 21, 2025

Record last verified: 2011-11

Locations

US (1)