NCT01105104

Brief Summary

The goal of the Enhanced Medication Management Program (eMMp) being developed by MedMinder Systems, Inc. is to increase the ability of frail elders to adhere to complex medication regimens for chronic conditions. Adherence will facilitate effective self-care and decrease personal and societal costs associated with disease progression and loss of independence. Multiple studies have shown that more frequent personal follow-up is the most effective way to maximize medication adherence, but such personal care is too costly to translate well to real life in a world of limited healthcare resources. Currently available "smart pillboxes" are too expensive, too limited in the number and types of medications delivered, and too technically complex for the large majority of senior citizens. The eMMp is designed to deliver prompts and reminders to the user, to be remotely programmable by caregivers, to allow the option of using pre-filled medication trays, to provide electronic adherence reports to family/caregivers and to provide personalized reinforcing phone calls from professional caregivers, all at a modest cost. The in-home ReMinder will use a familiar pillbox layout (4 doses/day for 7 days) and allow easy removal of medication cups by elderly, rheumatic fingers. Installation will require only an electrical outlet (no modems or dedicated phone lines). Once plugged in, the built-in pager will continuously download remotely programmed visual and/or aural prompts and reminders from a central server (RemoteMind). It will continuously upload the date and time when each medi-cation cup is removed and when weekly refill is carried out, enabling remote adherence monitoring, alerts to caregivers, and follow-up intervention(s) from personal and/or professional caregivers as needed. The hypothesis to be tested in this 2 year SBIR Phase I work plan is that the eMMp will significantly im-prove adherence and clinical outcome (blood pressure control) in a population of frail elderly who are hyper-tensive. SBIR Phase II will determine the minimum level of intervention needed to achieve sustained medication adherence and control of blood pressure in a larger group of hypertensive elders.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Sep 2011

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 14, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 16, 2010

Completed
1.4 years until next milestone

Study Start

First participant enrolled

September 1, 2011

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2013

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2013

Completed
Last Updated

November 8, 2011

Status Verified

November 1, 2011

Enrollment Period

1.7 years

First QC Date

April 14, 2010

Last Update Submit

November 7, 2011

Conditions

Outcome Measures

Primary Outcomes (2)

  • medication adherence

    6 months

  • change in systolic blood pressure

    6 months

Secondary Outcomes (2)

  • change in self-efficacy about taking medication

    6 months

  • self-reported medication taking

    6 months

Study Arms (2)

MedMinder System

OTHER
Device: MedMinder System

MedMinder System - deactivated

OTHER
Device: MedMinder System - deactivated

Interventions

Participants will receive a fully activated reminder unit as well as at least one call per month from a counselor.

MedMinder System

Participants will receive a one-way reminder unit that will remotely transit information on medication adherence

MedMinder System - deactivated

Eligibility Criteria

Age55 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • persons aged 55 years and older who are coming in for routine outpatient visits
  • speaks and reads English
  • history of high blood pressure
  • systolic blood pressure ≥ 130 mm Hg
  • using antihypertensive medication
  • using 2 or more prescription medications
  • plans to stay in area for the 9 months of study

You may not qualify if:

  • receives personal help or reminders to take medication
  • has moderate to severe dementia (MMSE score\<18)
  • has severe hearing or vision deficiency

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VA New York Harbor Healthcare System

New York, New York, 10010, United States

RECRUITING

MeSH Terms

Conditions

Medication AdherenceHypertension

Condition Hierarchy (Ancestors)

Patient CompliancePatient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehaviorVascular DiseasesCardiovascular Diseases

Central Study Contacts

Sundar Natarajan, MD, M.Sc

CONTACT

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 14, 2010

First Posted

April 16, 2010

Study Start

September 1, 2011

Primary Completion

May 1, 2013

Study Completion

June 1, 2013

Last Updated

November 8, 2011

Record last verified: 2011-11

Locations