Evaluation of Oxidative Stress and Effect of Levothyroxine Treatment on Oxidative Stress in Hashimoto Disease
1 other identifier
observational
130
1 country
1
Brief Summary
Oxidative stress leads to or accompanies with numerous disease. Oxidative balance in subclinical hypothyroid or euthyroid state in Hashimoto disease are not known. Effect of levothyroxine therapy on oxidative balance are also not known in hashimoto disease.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Apr 2010
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2010
CompletedFirst Submitted
Initial submission to the registry
April 9, 2010
CompletedFirst Posted
Study publicly available on registry
April 13, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2010
CompletedJune 13, 2013
June 1, 2013
Same day
April 9, 2010
June 11, 2013
Conditions
Outcome Measures
Primary Outcomes (1)
Poxidative stress markers
After levotren therapy
Study Arms (3)
healthy
euthyroid hashimoto
hypothyroid hashimoto
Eligibility Criteria
adult with Hashimoto disease in euthyroid or subclinical hypothyroid state and healthy control.
You may qualify if:
- age more than 18 years
You may not qualify if:
- inability to give a written consent
- other conditions and drug usage affect oxidative stress
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Vakif Gureba Training and Research Hospital
Istanbul, 34100, Turkey (Türkiye)
Biospecimen
after overnight fasting state,venous blood will be taken to obtain serum.speciemens stored -70 cantigrade celcius untillanalysing.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Mehmet ali Cikrikcioglu, MD
vakif gureba TRH,fatih,istanbul,turkey.specialist in internal medicine
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Vakif Gureba TRH
Study Record Dates
First Submitted
April 9, 2010
First Posted
April 13, 2010
Study Start
April 1, 2010
Primary Completion
April 1, 2010
Study Completion
October 1, 2010
Last Updated
June 13, 2013
Record last verified: 2013-06