NCT01093352

Brief Summary

The purpose of this pilot clinical trial is to evaluate whether alveolar-decortication has the potential to reduce orthodontic treatment time following surgical exposure of palatally impacted canines.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2010

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 23, 2010

Completed
23 days until next milestone

First Submitted

Initial submission to the registry

March 18, 2010

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 25, 2010

Completed
4.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2015

Completed
2.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 25, 2017

Completed
Last Updated

October 11, 2018

Status Verified

October 1, 2018

Enrollment Period

5 years

First QC Date

March 18, 2010

Last Update Submit

October 10, 2018

Conditions

Keywords

Alveolar-decorticationCorticotomy assisted orthodonticsPalatally impacted canineSurgical exposure of caninesVelocity of tooth movement

Outcome Measures

Primary Outcomes (1)

  • Velocity of tooth movement

    The velocity of movement of the canine tooth will be recorded, from the start (buried) position until it is in the line of the arch. Measurements will be taken at each orthodontic appointment, usually 6-8 weeks apart throughtout treatment. Distance will be measured with the use of linear measurements, impressions and clinical photographs.

    6-8 weeks

Secondary Outcomes (4)

  • Time for alignment

    approx. 2 years.

  • Total orthodontic treatment time

    approx. 2.5 years.

  • Duration of surgery

    1 day

  • Adverse effects of surgery

    approx. 2.5 years.

Study Arms (2)

Standard

NO INTERVENTION

Standard expose and bond.

Alveolar-decortication

EXPERIMENTAL

Following surgical exposure of the impacted canine, additional perforations will be made in the surrounding cortical bone prior to wound closure.

Procedure: Alveolar-decortication.

Interventions

Following surgical exposure of the impacted tooth, the surgeon will prepare small holes (perforations) and/or grooves in the cortical bone surrounding the exposed tooth as well as in the buccal bone.

Also known as: Alveolar-decortication, Corticotomy assisted orthodontics
Alveolar-decortication

Eligibility Criteria

Age10 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients at Birmingham Dental Hospital.
  • Patients with a palatally impacted canine, awaiting surgical exposure.
  • Patients with bilateral impacted canines may be included; in these cases both canines will be treated using the same surgical technique determined by allocation into either the test or control group.
  • Informed consent gained.

You may not qualify if:

  • History of periodontal disease.
  • Radiographical evidence of pathology associated with the impacted canine.
  • Patients already participating in a research study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

School of Dentistry, University of Birmingham

Birmingham, B4 6NN, United Kingdom

Location

Study Officials

  • Thomas Dietrich, DMD, MD, MPH

    School of Dentistry, University of Birmingham.

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
SpR in orthodontics

Study Record Dates

First Submitted

March 18, 2010

First Posted

March 25, 2010

Study Start

February 23, 2010

Primary Completion

March 1, 2015

Study Completion

October 25, 2017

Last Updated

October 11, 2018

Record last verified: 2018-10

Locations