Stiffness of the Skin and Joints in Relation to Carpal Tunnel Syndrome
STIF-CTS
Correlation of Joint Stiffness and Stiffness of the Skin and the Prevelation of Carpal Tunnel Syndrome (CTS)
1 other identifier
observational
40
1 country
1
Brief Summary
The exact etiology of CTS remains yet unknown. A rise in carpal tunnel pressure is well documented, but why this phenomenon occurs is yet unknown in most patients. There is an absolute or relative narrowing of the carpal tunnel, which results in a compression of the median nerve. The investigators postulate, that a stiffer flexor retinaculum (roof of carpal tunnel) will be less compliant. As a consequence of this stiffer retinaculum the pressure in the carpal tunnel will rise more quickly in stiff patients resulting in CTS-complaints. A relation between connective tissue composition and joint stiffness is proven. This relationship possibly extends to a relation between stiffness of the skin, joint stiffness and the prevalence of CTS.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started May 2010
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 2, 2010
CompletedFirst Posted
Study publicly available on registry
March 5, 2010
CompletedStudy Start
First participant enrolled
May 1, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2010
CompletedApril 27, 2010
April 1, 2010
6 months
March 2, 2010
April 26, 2010
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Joint stiffness
The active range of motion (elbow, wrist, knee and ankle) is measured with a standard goniometer.
In the 1st month
Stiffness of the skin
Skinstiffness is measured with a suction cup
in the 1st month
Secondary Outcomes (1)
Physical activities
In the 1st month
Study Arms (4)
Carpal tunnel syndrome
Patients with carpal tunnel syndrome
Trigger finger
Patients with trigger fingers
Dupuytren Contracture
Patients with Dupuytren
Trauma to the hand
Patients with an acute trauma to the hand
Eligibility Criteria
Patients presenting with complaints of: * Carpal tunnel syndrome * Trigger finger * Dupuytren contracture * an acute trauma to the hand
You may qualify if:
- Caucasian
- Carpal tunnel release OR Trigger finger OR Dupuytren OR an acute trauma to the hand
You may not qualify if:
- Hypo-/hyperthyroidism
- Diabetes
- Arthritis
- Pregnancy
- Obesity (BMI \>30)
- Anatomical anomalies
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
St Antonius Hospital
Nieuwegein, Utrecht, 3430EM, Netherlands
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
A.B. Mink van der Molen, dr.
St. Antonius Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
March 2, 2010
First Posted
March 5, 2010
Study Start
May 1, 2010
Primary Completion
November 1, 2010
Study Completion
December 1, 2010
Last Updated
April 27, 2010
Record last verified: 2010-04