NCT01073046

Brief Summary

The purpose of this study is to test the utility of the nasogastric tube, which is used to decompress and as "guardian" of gastro-jejunal anastomosis, in patients undergoing distal subtotal gastrectomy for gastric cancer with reconstruction according to Billroth II or according Roux.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
276

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2010

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2010

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 1, 2010

Completed
22 days until next milestone

First Posted

Study publicly available on registry

February 23, 2010

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2012

Completed
Last Updated

August 2, 2012

Status Verified

January 1, 2010

Enrollment Period

2.4 years

First QC Date

February 1, 2010

Last Update Submit

August 1, 2012

Conditions

Keywords

Naso-Gastric/Jejunal TubeSub-total GastrectomyGastric CancerDecompressionDiscomfortComplications

Outcome Measures

Primary Outcomes (1)

  • Influence of Naso-Gastric/Jejunal Tube on Postoperative complications

    2 years

Secondary Outcomes (1)

  • Influence of Naso-Gastric/Jejunal Tube on Postoperative Patient's Comfort

    2 years

Study Arms (2)

Place Naso-Gastric/Jejunal Tube Group

In this group a silastic naso-gastric/jejunal tube is placed (Rusch® distributed by Teleflex Medical Srl)

Device: Naso-Gastric/Jejunal Tube

No Naso-Gastric/Jejunal Tube Group

In this group a silastic naso-gastric/jejunal tube is not placed

Interventions

Silastic Naso-Gastric/Jejunal Tube (Rusch® distributed by Teleflex Medical Srl)

Also known as: Rusch® distributed by Teleflex Medical Srl
Place Naso-Gastric/Jejunal Tube Group

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients will be included, using a randomization list provided to each center, in one of two groups: 1. placement of a polyurethane nasogastric/jejunal tube, preferentially 12-14 Fr; 2. no feeding tube placement.

You may qualify if:

  • All people subjected to subtotal gastrectomy for distal gastric adenocarcinoma.

You may not qualify if:

  • People undergoing enteral nutrition through naso-jejunal tube

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Digestive Surgery, Catholic University

Rome, 00168, Italy

Location

Related Publications (1)

  • Pacelli F, Rosa F, Marrelli D, Morgagni P, Framarini M, Cristadoro L, Pedrazzani C, Casadei R, Cozzaglio L, Covino M, Donini A, Roviello F, de Manzoni G, Doglietto GB. Naso-gastric or naso-jejunal decompression after partial distal gastrectomy for gastric cancer. Final results of a multicenter prospective randomized trial. Gastric Cancer. 2014 Oct;17(4):725-32. doi: 10.1007/s10120-013-0319-x. Epub 2013 Nov 30.

MeSH Terms

Conditions

Stomach Neoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesStomach Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

February 1, 2010

First Posted

February 23, 2010

Study Start

January 1, 2010

Primary Completion

June 1, 2012

Study Completion

June 1, 2012

Last Updated

August 2, 2012

Record last verified: 2010-01

Locations