NCT01072006|CompletedResults
Loading search results
Sponsor study identifier
observational
30
1 country
1
Study Start
June 7, 2011
Actual (reported)Primary Completion
December 1, 2015
Actual (reported)Study Completion
April 21, 2017
Actual (reported)This research investigates processes involved with one being able to focus on relevant information and ignore non-relevant information in veterans with PTSD and those with a history of traumatic brain injury. In addition, this study evaluates whether there is an additive effect of having both PTSD and history of TBI on ability to focus attention and inhibit distracting information.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
April 21, 2017
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
February 18, 2010
Actual (reported)February 19, 2010
Actual (reported)June 7, 2011
Actual (reported)December 1, 2015
Actual (reported)April 21, 2017
Actual (reported)April 24, 2017
Actual (reported)Functional Magnetic Resonance Imaging (fMRI) Correlation
Functional magnetic resonance imaging (fMRI) is used to measure neural activity in participants during attentional task, specifically measured as a bold signal change from rest to attention task. We then calculate the correlation between the bold signal (fMRI) and the PTSD CheckList questionnaire score. (The bold signal from fMRI indirectly reflects the brain's use of glucose, the brain's main energy source.) Correlations are reflected in an R-value, and R-values can range from 0-1, where 0 means there is no correlation (or relationship) between the two measures (here, the two measures are the fMRI brain signal and the PTSD score) and 1 means there is a perfect correlation between the two measures. A high correlation in this study would suggest that the more severe a patient's PTSD symptoms are, the harder their brain is having to work to accomplish the attention task. Separate correlations were analyzed for each group, and the overall R-value for each group is reported below.
These are chronic patients and controls who will only be tested at one time point, which corresponds to their entry into the study (after signing consent forms). Data collected at this single time point will be reported.
Psychodiagnostic Testing: Post-traumatic Stress Disorder Check List (PCL) Measures the Level of Post-traumatic Stress Disorder (PTSD) Symptoms
These are chronic patients and controls who will only be tested at one time point, which corresponds to their entry into the study (after signing consent forms). Data collected at this single time point will be reported.
Neuropsychological Testing (Wechsler Test of Adult Reading)
These are chronic patients and controls who will only be tested at one time point, which corresponds to their entry into the study (after signing consent forms). Data collected at this single time point will be reported.
Control group without traumatic brain injury (TBI) or post-traumatic stress disorder (PTSD)
PTSD (not TBI)
TBI (no PTSD)
Combined TBI history and PTSD
OEF/OIF Veterans enrolled in the Northern California Health Care System
Martinez Outpatient Clinic and Community Living Center, Martinez, CA
Martinez, California, 94553, United States
Sozda CN, Muir JJ, Springer US, Partovi D, Cole MA. Differential learning and memory performance in OEF/OIF veterans for verbal and visual material. Neuropsychology. 2014 May;28(3):347-352. doi: 10.1037/neu0000043. Epub 2013 Nov 18.
Juliana V. Baldo, PhD
Martinez Outpatient Clinic and Community Living Center, Martinez, CA
30 participants (actual enrollment reported by the registry).
First Submitted
February 18, 2010
First Posted
February 19, 2010
Study Start
June 7, 2011
Actual (reported)Contact the study team to confirm eligibility.
Primary Completion
December 1, 2015
Actual (reported)Study Completion
April 21, 2017
Actual (reported)Last Updated
September 12, 2017
Results First Posted
April 24, 2017
Record last verified: 2017-08
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: