The Development of Allergic Rhinitis in Children Previously Diagnosed as Nonallergic Rhinitis

NCT01068808 | Completed DMC

• 1 other identifier: 640/2552(EC4)
• Study Type: observational
• Target: 175
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to evaluate development of allergic rhinitis in children with nonallergic rhinitis.

Conditions

Allergic Rhinitis (Disorder)

Keywords

Nonallergic rhinitis; Allergic rhinitis; Development

Outcome Measures

Primary Outcomes (1)

• To evaluate the development of AR in children who were previously diagnosed with NAR

  24 months

Secondary Outcomes (1)

• To determine the persistence and severity of the symptoms, new comorbidities and triggering factors in children with nonallergic rhinitis

  24 months

Study Arms (1)

Nonallergic rhinitis

Nonallergic rhinitis (negative skin prick test)

Procedure: skin prick test

Interventions

skin prick test PROCEDURE

skin prick test to aeroallergen

Also known as: SPT

Nonallergic rhinitis

Eligibility Criteria

• Age: 1 Year - 15 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

The patient from pediatric allergy clinic will be selected.

You may qualify if:

• Children between the age of 1 year and 15 years with the diagnosis of nonallergic rhinitis who are attending the pediatric allergy clinic during Jan 2005 - Dec 2007.

You may not qualify if:

• Patients who have allergic rhinitis and underlying disease eg.chronic renal disease, liver disease, heart disease, cancer.

Sponsors & Collaborators

• Mahidol University: lead

Study Sites (1)

Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University

Bangkok, Bangkok, 10700, Thailand

Location

Related Publications (1)

• Veskitkul J, Vichyanond P, Visitsunthorn N, Jirapongsananuruk O. The development of allergic rhinitis in children previously diagnosed as nonallergic rhinitis. Am J Rhinol Allergy. 2013 Jan;27(1):43-7. doi: 10.2500/ajra.2013.27.3839.

  PMID: 23406600 RESULT

MeSH Terms

Conditions

Rhinitis, Allergic

Interventions

Patch Tests

Condition Hierarchy (Ancestors)

Rhinitis; Nose Diseases; Respiratory Tract Diseases; Respiratory Hypersensitivity; Otorhinolaryngologic Diseases; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Intervention Hierarchy (Ancestors)

Skin Tests; Immunologic Tests; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Investigative Techniques; Immunologic Techniques

Study Officials

• Orathai Piboonpocanun, Assoc.Prof.

  Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Department of Pediatrics, Faculty of medicine, Siriraj hospital

Study Record Dates

• First Submitted: February 12, 2010
• First Posted: February 15, 2010
• Study Start: January 1, 2010
• Primary Completion: June 1, 2012
• Study Completion: August 1, 2012
• Last Updated: February 20, 2013

Record last verified: 2013-02

Locations

TH (1)