NCT01063608|CompletedPhase 4
Study of Immune Responses After Vaccination Against Seasonal Influenza Virus and Against Influenza H1N1-v Pandemic Virus in a Medical Staff.
FLU-HOP
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FLU-HOP
Sponsor study identifier
Secondary identifiers
EUDRACT_NUMBER
NIH
interventional
147
1 country
2
Study Start
October 2009
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2009
Actual (reported)Study Completion
May 2010
Actual (reported)This project may help to answer several fundamental questions related to public health regarding vaccination against influenza viruses and regarding the influenza A(H1N1)v pandemy: What is the immunologic efficacy in terms of antibodies response of the vaccination against the seasonal (2009-2010) influenza virus and against the A(H1N1)v virus in the clinical staff? Moreover, it may help to answer questions related to the use of a vaccine against influenza virus variants emerging in the French population:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 2010
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 2009
Date type not reportedThis date has not been verified as actual or estimated.
December 2009
Actual (reported)February 4, 2010
Actual (reported)February 5, 2010
Actual (reported)May 2010
Actual (reported)Evaluation of the intensity of the humoral and cellular immune responses of the anti-A(H1N1)v vaccine in a medical care population as a function of the age and of the prior seasonal anti-influenza vaccinations.
5 months
Investigate the quality of the humoral and cellular immune responses induced by the seasonal anti-influenza vaccine as a function of the age and of the prior seasonal vaccinations.
5 months
Determine the cross-reactivity of the humoral and cellular immune responses as a function of the age and of the prior seasonal vaccinations
5 months
Assess the tolerance to the seasonal and pandemic vaccines
5 months
Assess the occurence of flu episodes and their severity during the 2009-2010 season as a function of the age of the population. Then, the correlation between the flu episodes and and the immunologic results is to be evaluated.
5 months
Evaluate the perception of the anti-influenza vaccination in a medical care population in the current H1N1v pandemy context.
5 months
Inclusion of hospital personnel in the context of the anti-H1N1v prophylaxy plan.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Hopital Pitie Salpetriere
Paris, Île-de-France Region, 75013, France
Centre d'Investigations Cliniques (CIC), Hopital Cochin
Paris, Île-de-France Region, 75014, France
Bonduelle O, Yahia N, Siberil S, Benhabiles N, Carrat F, Krivine A, Rozenberg F, Dimitrov J, Kaveri SV, Curjol A, Tindel M, Louet M, Desert F, Launay O, Loulergue P, Badre G, Katlama C, Bricaire F, Samri A, Rousset D, van der Werf S, Jaureguiberry S, Combadiere B. Longitudinal and integrative biomodeling of effector and memory immune compartments after inactivated influenza vaccination. J Immunol. 2013 Jul 15;191(2):623-31. doi: 10.4049/jimmunol.1203483. Epub 2013 Jun 17.
Stephane Jaureguiberry, MD
Groupe Hospitalier Pitie-Salpetriere
Behazine Combadiere, PhD
INSERM U945
147 participants (actual enrollment reported by the registry).
First Submitted
February 4, 2010
First Posted
February 5, 2010
Study Start
October 2009
Date type not reportedThis date has not been verified as actual or estimated.
Crossover Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Repeat Dose Zanamivir/Placebo Via Devices Administered Twice Daily for 5 Days
Contact the study team to confirm eligibility.
Primary Completion
December 2009
Actual (reported)Study Completion
May 2010
Actual (reported)Last Updated
October 9, 2026
Record last verified: 2010-03
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Source: ClinicalTrials.gov.
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