An Epidemiological Study of Acute Coronary Syndromes in The Greek Population. The TARGET Study
TARGET
1 other identifier
observational
418
1 country
11
Brief Summary
This is a multicenter, 2-phase observational study of acute coronary syndromes (ACS) in Greece, designed to provide real world data on the risk factors of patients presenting to a hospital emergency department with an index event, as well as to depict the current management practices and outcomes of these clinical conditions in Greece.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2010
11 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2010
CompletedFirst Submitted
Initial submission to the registry
February 1, 2010
CompletedFirst Posted
Study publicly available on registry
February 2, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2011
CompletedDecember 21, 2011
December 1, 2011
5 months
February 1, 2010
December 20, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
To evaluate the proportion of patients who are on target for LDL-C according to the 2004-updated NCEP ATPIII guidelines as calculated within the first 24-hours of hospital admission for an ACS.
first visit - 1st day (cross-sectional part)
To estimate the proportion of patients enrolled in the cross-sectional part of the study that experiences a Major Adverse Cardiovascular Event (MACE) within a 6-month follow-up period.
follow up visit - 6th month (prospective part)
Secondary Outcomes (3)
To estimate the proportion of patients admitted to the hospital with STEMI, NSTEMI and unstable angina.
first visit - 1st day (cross-sectional part)
To estimate the "pain-to-door-time" throughout different regions in Greece.
first visit - 1st day (cross-sectional part)
To estimate the time to first MACE and to estimate CV, non-CV and all cause mortality within the 6-month period following the index ACS event.
follow up visit - 6th month (prospective part)
Study Arms (1)
1
Patients over 18 years old admitted to the hospital with Acute Coronary Syndrome.
Eligibility Criteria
Emergency Room
You may qualify if:
- Diagnosis of an ACS (STEMI, NSTEMI, UA).
- Informed Consent
You may not qualify if:
- Involvement in the planning and conduct of the study (applies to both AstraZeneca staff and staff at the study sites).
- Participation in other clinical study in period between the index event and 6- month follow-up assessment with the exception of registering in registries or surveys not influencing the management of the ACS.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- AstraZenecalead
- Hellenic Cardiovascular Research Societycollaborator
Study Sites (11)
Research Site
Athens, Attica, Greece
Research Site
Chalcis, Chalkida, Greece
Research Site
Chania, Chanion, Greece
Research Site
Chios, Chios, Greece
Research Site
Heraklion, Herakliou, Greece
Research Site
Ioannina, Ioanninon, Greece
Research Site
Ptolemaida, Kozani, Greece
Research Site
Larissa, Larrisis, Greece
Research Site
Volos, Magnisias, Greece
Research Site
Eddesa, Pella, Greece
Research Site
Komotini, Rodopi, Greece
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Panagiotis Pontikis
AstraZeneca
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 1, 2010
First Posted
February 2, 2010
Study Start
January 1, 2010
Primary Completion
June 1, 2010
Study Completion
February 1, 2011
Last Updated
December 21, 2011
Record last verified: 2011-12