NCT01059032

Brief Summary

Through the rapid growth of multislice Computer Tomography (CT) imaging, radiation protection has become a major issue in the radiological community. Optimizing CT scanning is a key task when keeping the radiation doses as low as reasonable achievable (the ALARA principle). Post processing filters can improve and restore grainy and noisy low dose CT images by enhancing structure and reducing image noise. In our study of 10 patients, the investigators perform a preliminary evaluation of a novel post processing filter, which does picture element correlations in all three spatial dimensions. By comparing normal dose pictures with unprocessed low-dose pictures and pictures processed with two dimentional (2D) and three dimentional (3D) filters,the investigators will be able to assess the possible clinical value of the 3D filter. This project is collaboration between Buskerud Hospital (BU), Buskerud University College, Norwegian Radiation Protection Authority (NRPA) and Center for Medical Image Science and Visualization (CMIV). The project is part of the PhD of Lars Borgen.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for phase_1

Timeline
Completed

Started Dec 2009

Typical duration for phase_1

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2009

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

January 21, 2010

Completed
8 days until next milestone

First Posted

Study publicly available on registry

January 29, 2010

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2010

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2011

Completed
Last Updated

June 2, 2015

Status Verified

November 1, 2009

Enrollment Period

1 year

First QC Date

January 21, 2010

Last Update Submit

June 1, 2015

Conditions

Radiation Protection

Outcome Measures

Primary Outcomes (1)

  • Rating of image quality

    3-6 months

Study Arms (2)

Unenhanced images

NO INTERVENTION

Enhanced images

OTHER

Enhanced images

Other: Using a 3 dimentional post processing filter

Interventions

Using a 3 dimentional post processing filterOTHER

Using a 3 dimentional post processing filter

Enhanced images

Eligibility Criteria

Age60 Years - 90 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Outpatients, Male or female,Age above 60 years, Referred to our department for an abdominal CT with intravenous contrast.

You may not qualify if:

  • Abdominal diameter less than 80cm or larger than 100cm, Gross pancreatic pathology, Gross anatomic anomalies in the investigated region, Intolerance of intravenous contrast

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Buskerud Hospital

Drammen, 3014, Norway

Location

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

January 21, 2010

First Posted

January 29, 2010

Study Start

December 1, 2009

Primary Completion

December 1, 2010

Study Completion

December 1, 2011

Last Updated

June 2, 2015

Record last verified: 2009-11

Locations

NO(1)