Nurse Managed Upper Body Strength Training in Chronic Obstructive Pulmonary Disease (COPD)

NCT01057797 | Completed Phase 2

• 1 other identifier: NR08037
• Study Type: interventional
• Target: 208
• Locations: 1 country
• Sites: 1

Brief Summary

This is a four month exercise training program for people with chronic obstructive pulmonary disease (COPD)with a 12 month follow-up.

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

COPD; Pulmonary rehabilitation; Self-efficacy; Muscle strength; Dyspnea; Exercise adherence

Outcome Measures

Primary Outcomes (3)

• Upper body strength

  before training, after training, 6 months post training, 12 months post training

• Dyspnea

  before training, after training, 6 months post training, 12 months post training

• Functional performance

  before training, after training, 6 months post training, 12 months post training

Secondary Outcomes (1)

• Exercise adherence

  before training, after training

Study Arms (3)

Upper Body Strength Training with Self-Efficacy

EXPERIMENTAL

16 weeks of upper body strength training combined with an exercise-specific self-efficacy enhancing intervention

Behavioral: Exercise-specific self-efficacy; Behavioral: upper body strength training

Upper body strength training

ACTIVE COMPARATOR

16 weeks of upper body strength training with weekly health education sessions

Behavioral: upper body strength training

Chair exercise

SHAM COMPARATOR

16 wks of gentle chair exercise with weekly health education

Behavioral: Gentle chair exercise

Interventions

Exercise-specific self-efficacy BEHAVIORAL

Subjects in the experimental group will participate in a self-efficacy enhancing intervention designed to maximize (a) exercise-specific SE-UB strength training (b) self-efficacy for overcoming barriers to exercise and (c) SE-UB physical activities. The intervention incorporates strategies to maximize the primary sources of efficacy information: (a) mastery accomplishments, (b) social modeling, (c) social persuasion, (d) interpretation of physiological and affective symptoms.

Upper Body Strength Training with Self-Efficacy

Gentle chair exercise BEHAVIORAL

Gentle armchair fitness exercises will be used as a sham treatment to control for the attention that subjects receive in the two strength training groups. The armchair fitness exercises will be conducted in small groups (n=8-10 per group). Armchair exercises will include stretching of all major joints with an emphasis on the arms and shoulders, massage of muscles that can be reached from the armchair (scalp, neck, shoulders, lower back, abdomen and thighs) and imagery to promote relaxation. Each session will include: 5 minutes of slow stretching, 20 minutes of faster paced exercises, 5 minutes of slower paced stretches, followed by 5-10 minutes of massage and imagery for relaxation.

Chair exercise

upper body strength training BEHAVIORAL

16 weeks of lab-based upper body strength training using 8: modified lateral pull down, shoulder shrug, upright row, overhead pull down, front raise, front pull down, triceps extension, biceps curl. Training load and volume will be increased progressing from 70% to 80% of the maximum strength training and from 2 sets of 8-10 repetitions progressing to 3 sets. Each week subjects will train twice in the lab and once at home. Home exercises will include 1 set of 15-20 repetitions: biceps curl, triceps extension, front raises, lateral raises, overhead press, chest press and one-arm dumbbell row.

Upper Body Strength Training with Self-Efficacy; Upper body strength training

Eligibility Criteria

• Age: 45 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• FEV1/FVC \< 70 and FEV1 \< 80%
• \> or = 45 years of age
• Currently in stable clinical condition \[free of respiratory tract infections for at least two months prior to enrollment, no recent change in the color, consistency, or quantity of sputum, afebrile and no recent change in medical therapy\]
• Taking appropriate medications according to the GOLD standards
• Experience dyspnea with the use of their arms.

You may not qualify if:

• Evidence of restrictive lung disease or asthma
• Acute respiratory infection
• Taking oral corticosteroids on a regular basis
• \>3 exacerbations in the previous year
• Evidence of significant depression (Hospital Anxiety Depression Scale \>10)
• Presence of a potentially debilitating disease such as cancer, congestive heart failure, kidney disease, liver failure or cirrhosis, evidence of alcohol or drug abuse, diabetes requiring insulin therapy, musculoskeletal or degenerative nerve disease, etc.
• Presence of a condition that would make it potentially unsafe to exercise, including a history of a recent myocardial infarction, unstable angina pectoris, uncontrolled cardiac arrhythmias causing symptoms or hemodynamic compromise, severe symptomatic aortic stenosis, uncontrolled symptomatic heart failure, uncontrolled metabolic disease, abnormal response to exercise test
• Currently participating in pulmonary rehabilitation.

Sponsors & Collaborators

• University of Illinois at Chicago: lead

Study Sites (1)

University of Illinois at Chicago

Chicago, Illinois, 60612, United States

Location

Related Publications (1)

• Larson JL, Covey MK, Kapella MC, Alex CG, McAuley E. Self-efficacy enhancing intervention increases light physical activity in people with chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2014 Oct 3;9:1081-90. doi: 10.2147/COPD.S66846. eCollection 2014.

  PMID: 25336939 DERIVED

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Dyspnea

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Respiration Disorders; Signs and Symptoms, Respiratory; Signs and Symptoms

Study Officials

• Janet L Larson, PhD, RN

  University of Illinois at Chicago and University of Michigan

  PRINCIPAL INVESTIGATOR

• Margaret K Covey, PhD, RN

  University of Illinois at Chicago

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: phase 2
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: January 26, 2010
• First Posted: January 27, 2010
• Study Start: September 1, 2003
• Primary Completion: January 1, 2009
• Study Completion: January 1, 2009
• Last Updated: January 27, 2010

Record last verified: 2010-01

Locations

US (1)