NCT01057719

Brief Summary

The aim of the study was to compare the effect of inpatient physiotherapy in a warm climate versus physiotherapy in a colder climate in multiple sclerosis (MS), in both short- and long term perspectives.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P50-P75 for not_applicable multiple-sclerosis

Timeline
Completed

Started Jun 2006

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2006

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2008

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

January 26, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 27, 2010

Completed
Last Updated

January 27, 2010

Status Verified

January 1, 2010

Enrollment Period

1.9 years

First QC Date

January 26, 2010

Last Update Submit

January 26, 2010

Conditions

Keywords

cross-over designmixed modelmultiple sclerosisphysical performance measuresphysical therapythe Bobath conceptwarm climate6-minute walk test

Outcome Measures

Primary Outcomes (1)

  • 6-minute walk test

    2 years

Secondary Outcomes (10)

  • Timed Up&Go

    2 years

  • 10-metre timed walk

    2

  • Berg Balance Scale

    2

  • Trunk Impairment Scale

    2

  • Borg's Rating of Perceived Exertion

    2

  • +5 more secondary outcomes

Study Arms (2)

Physiotherapy in Spain

EXPERIMENTAL

Daily inpatient physiotherapy for four weeks in a warm climate

Other: Physiotherapy

Physiotherapy in Norway

EXPERIMENTAL

Daily inpatient physiotherapy for four weeks in a cold climate

Other: Physiotherapy

Interventions

Individual tailored physiotherapy according to the Bobath concept sixty minutes each working day for four weeks

Also known as: Physical Therapy, Subtropical climate
Physiotherapy in NorwayPhysiotherapy in Spain

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Between 18 and 60 years of age (both included).
  • Multiple sclerosis according to the McDonald criteria
  • Disability equivalent to Expanded Disability Status Score (EDSS) between 4.0 and 6.5 (both included)
  • Prepared to and considered able to follow the protocol and to attend the planned visits during the whole study period.
  • Given written informed consent

You may not qualify if:

  • Excessive fatigue or severe cognitive dysfunction related to MS that would preclude safe participation in the protocol.
  • Suffered from major depression or any other psychiatric disorder that would preclude safe participation in the protocol.
  • Heat intolerance.
  • Other serious concomitant disease that could preclude safe participation in the protocol.
  • Alcohol or drug abuse or consumption that could preclude participation according to the protocol and to attend the planned visits during the whole study period.
  • Breastfeeding or pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Haukeland University Hospital

Bergen, 5021, Norway

Location

MeSH Terms

Conditions

Multiple Sclerosis

Interventions

Physical Therapy Modalities

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNSAutoimmune Diseases of the Nervous SystemNervous System DiseasesDemyelinating DiseasesAutoimmune DiseasesImmune System Diseases

Intervention Hierarchy (Ancestors)

TherapeuticsRehabilitation

Study Officials

  • Tori Smedal, MSc

    Haukeland University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER

Study Record Dates

First Submitted

January 26, 2010

First Posted

January 27, 2010

Study Start

June 1, 2006

Primary Completion

May 1, 2008

Study Completion

May 1, 2008

Last Updated

January 27, 2010

Record last verified: 2010-01

Locations