NCT01055951

Brief Summary

The purpose of this study is to assess the safety and usability of the Solo™ insulin MicroPump in subjects with type 1 diabetes who are pump users.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started May 2009

Typical duration for phase_1

Geographic Reach
2 countries

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2009

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

January 24, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 26, 2010

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2011

Completed
Last Updated

June 2, 2011

Status Verified

June 1, 2011

Enrollment Period

2.1 years

First QC Date

January 24, 2010

Last Update Submit

June 1, 2011

Conditions

Keywords

Insulin pumpsDiabetes

Outcome Measures

Primary Outcomes (1)

  • Device-related adverse outcome

    During treatment period

Secondary Outcomes (1)

  • Mechanical dysfunction and diabetes-related adverse outcome

    During treatment period

Study Arms (1)

Solo MicroPump

EXPERIMENTAL
Device: Solo MicroPump

Interventions

30 days treatment days with an optional extension period of up to 6 month of treatment.

Also known as: Solo System
Solo MicroPump

Eligibility Criteria

Age16 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Age range of:
  • to 60 years in Israel
  • to 60 years in Austria
  • Type I diabetes and pump treatment duration of more than 6 months.
  • Subjects who are using Humalog®, NovoRapid®, and Apidra® 100U/ml insulin
  • Measures glucose at least four times per day.
  • No more than one severe hypoglycemic or ketoacidosis episode within one year
  • Willing to sign an informed consent.
  • Cooperative, willing to attend all study visits.

You may not qualify if:

  • A1c \>= 10.0%
  • Two or more documented events of severe hypoglycemia within the previous 12 months
  • Diabetes related hospitalization over the past 12 months
  • Current significant diabetes-related complications
  • Pregnant, lactating or planning to become pregnant during the course of the study
  • Substance or alcohol abuse
  • Uncontrolled hypertension
  • Known dermal hypersensitivity to medical adhesive
  • Recurrent episodes of skin infections or dermatological allergies
  • Serious or unstable medical or psychological conditions
  • Current participation in other clinical studies.
  • Working for a competitor company

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Medical University Graz

Gratz, A - 8036, Austria

Location

Rambam Healthcare Campus

Haifa, 31096, Israel

Location

Sourasky Medical Center

Tel Aviv, Israel

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 1Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Study Design

Study Type
interventional
Phase
phase 1
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

January 24, 2010

First Posted

January 26, 2010

Study Start

May 1, 2009

Primary Completion

June 1, 2011

Study Completion

June 1, 2011

Last Updated

June 2, 2011

Record last verified: 2011-06

Locations