NCT01054612|Withdrawn
Study Stopped
The study was closed due to the departure of several of the co-investigators.
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The study was closed due to the departure of several of the co-investigators.
Sponsor study identifier
Secondary identifiers
observational
0
0 countries
N/A
Study Start
March 2002
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
January 2010
Actual (reported)Study Completion
January 2010
Actual (reported)Currently there is no technique to produce thin (0.004-0.01 mm) serial sections of large fresh tissue specimens that are suitable for high-resolution in situ protein/gene expression studies without ice artifact or fixation-induced molecular damage. Traditional frozen sectioning preserves protein and nucleic acid structure, but the inherent ice artifact precludes reconstruction of protein and mRNA expression patterns in 3-dimensions. Since the limitations of the existing sectioning techniques result from the fact that they rely on mechanical cutting which in turn require the tissue to be stiff, we suggest a new approach to cut tissue via an electro erosion process that utilizes focus radio frequency (RF).
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 2010
Actual (reported)Click on a node to explore related trials.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 2002
Date type not reportedThis date has not been verified as actual or estimated.
December 21, 2007
Actual (reported)January 2010
Actual (reported)January 2010
Actual (reported)January 22, 2010
Actual (reported)Focused RF energy can be used to produce consecutive thin sections of fresh tissue for immunohistochemical and nucleic acids analysis by electro-dissociation without thermal damage, ultimately allowing high resolution reconstruction of gene and protein expression patterns of large tissue specimens in 3D.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Discarded human tissue obtained immediately following surgical resection
Gal Shafirstein, Ph.D.
UAMS, ACH, Central Arkansas Veterans Healthcare System
0 participants (actual enrollment reported by the registry).
First Submitted
December 21, 2007
First Posted
January 22, 2010
Study Start
March 2002
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Contact the study team to confirm eligibility.
January 2010
Actual (reported)Study Completion
January 2010
Actual (reported)Last Updated
March 4, 2015
Record last verified: 2015-03
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Source: ClinicalTrials.gov.
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