Sexually Transmitted Infections Among African American Women Who Have Sex With Women

NCT01043081 | Completed

• 1 other identifier: 2008-0143
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine the rates of sexually transmitted infections (STI) among a group of African American women who have sex with women (AA WSW). The first study hypothesis is that AA WSW are at risk for acquiring and transmitting STI, including the human immunodeficiency virus (HIV). The second study hypothesis is that AA WSW participate in multiple high-risk sexual activities that may facilitate transmission of STIs, including HIV.

Conditions

Sexually Transmitted Infections; HIV Infections

Keywords

African American women who have sex with women; Sexually transmitted infections; Homosexuality; Human papillomavirus; Cervical intraepithelial neoplasia; Herpes simplex virus types 1 and 2; Chlamydia; Gonorrhea; Trichomoniasis; Bacterial vaginosis; Syphilis; Human immunodeficiency virus

Outcome Measures

Primary Outcomes (1)

• Prevalence rates of sexually transmitted infections

  18 Months

Secondary Outcomes (1)

• Associated sexual risk behaviors

  18 Months

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population is African American women, aged 18 or above, who present to the Crossroads Clinic (STD Clinic) in the Jackson, MS metropolitan area for STI screening/evaluation who have engaged in sexual contact with another woman within the past 6 months.

You may qualify if:

• Female
• Age 18 years or older
• African American race
• Sexual contact with another female within the past 6 months
• Ability to give written informed consent

You may not qualify if:

• Male
• Age less than 18 years old
• Race other than African American
• No sexual contact with another woman within the past 6 months
• Pregnant
• Prior enrollment in this study
• Participants who, for any reason, in the opinion of the investigator, do not have the ability to give written informed consent or may not be expected to comply with the requirements of the protocol

Sponsors & Collaborators

• University of Mississippi Medical Center: lead
• Mississippi State Department of Health: collaborator
• University of Alabama at Birmingham: collaborator

Study Sites (1)

Crossroads Clinic

Jackson, Mississippi, 39216, United States

Location

Related Publications (5)

• Muzny CA, Sunesara IR, Griswold ME, Kumar R, Lefkowitz EJ, Mena LA, Schwebke JR, Martin DH, Swiatlo E. Association between BVAB1 and high Nugent scores among women with bacterial vaginosis. Diagn Microbiol Infect Dis. 2014 Dec;80(4):321-3. doi: 10.1016/j.diagmicrobio.2014.09.008. Epub 2014 Sep 16.

  PMID: 25262105 RESULT

• Muzny CA, Rivers CA, Parker CJ, Mena LA, Austin EL, Schwebke JR. Lack of evidence for sexual transmission of genital Candida species among women who have sex with women: a mixed methods study. Sex Transm Infect. 2014 Mar;90(2):165-70. doi: 10.1136/sextrans-2013-051361. Epub 2014 Jan 15.

  PMID: 24431188 RESULT

• Muzny CA, Sunesara IR, Kumar R, Mena LA, Griswold ME, Martin DH, Lefkowitz EJ, Schwebke JR, Swiatlo E. Characterization of the vaginal microbiota among sexual risk behavior groups of women with bacterial vaginosis. PLoS One. 2013 Nov 13;8(11):e80254. doi: 10.1371/journal.pone.0080254. eCollection 2013.

  PMID: 24236175 RESULT

• Muzny CA, Sunesara IR, Austin EL, Mena LA, Schwebke JR. Bacterial vaginosis among African American women who have sex with women. Sex Transm Dis. 2013 Sep;40(9):751-5. doi: 10.1097/OLQ.0000000000000004.

  PMID: 23949590 RESULT

• Muzny CA, Sunesara IR, Martin DH, Mena LA. Sexually transmitted infections and risk behaviors among African American women who have sex with women: does sex with men make a difference? Sex Transm Dis. 2011 Dec;38(12):1118-25. doi: 10.1097/OLQ.0b013e31822e6179.

  PMID: 22082722 RESULT

Biospecimen

Retention: SAMPLES WITH DNA

Endocervical and vaginal secretion specimens are being retained for future research studies in this field of sexually transmitted diseases.

MeSH Terms

Conditions

Sexually Transmitted Diseases; HIV Infections; Homosexuality; Uterine Cervical Dysplasia; Chlamydia Infections; Gonorrhea; Trichomonas Infections; Vaginosis, Bacterial; Syphilis; Acquired Immunodeficiency Syndrome

Condition Hierarchy (Ancestors)

Communicable Diseases; Infections; Genital Diseases; Urogenital Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Blood-Borne Infections; Sexually Transmitted Diseases, Viral; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Sexuality; Sexual Behavior; Behavior; Precancerous Conditions; Neoplasms; Uterine Cervical Diseases; Uterine Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Chlamydiaceae Infections; Gram-Negative Bacterial Infections; Bacterial Infections; Bacterial Infections and Mycoses; Sexually Transmitted Diseases, Bacterial; Neisseriaceae Infections; Protozoan Infections; Parasitic Diseases; Vaginitis; Vaginal Diseases; Treponemal Infections; Spirochaetales Infections; Slow Virus Diseases

Study Officials

• Leandro A Mena, MD, MPH

  University of Mississippi Medical Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Medicine

Study Record Dates

• First Submitted: January 4, 2010
• First Posted: January 6, 2010
• Study Start: February 1, 2009
• Primary Completion: December 1, 2011
• Study Completion: June 1, 2012
• Last Updated: May 11, 2016

Record last verified: 2016-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)