NCT01040182

Brief Summary

The purpose of this study is to explore the association between the genetic polymorphisms of estrogen-related genes, including estrogen synthesis, metabolizing, and receptor genes, and ischemic stroke. Furthermore, independent and joint effects of traditional risk factors and estrogen related genes on risk of stroke in young adults will also be examined in this study.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2009

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2009

Completed
26 days until next milestone

First Submitted

Initial submission to the registry

December 27, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 29, 2009

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2010

Completed
Last Updated

December 3, 2010

Status Verified

December 1, 2010

Enrollment Period

11 months

First QC Date

December 27, 2009

Last Update Submit

December 1, 2010

Conditions

Ischemic Stroke

Keywords

ischemic stroke patients

Study Arms (2)

ischemic stroke patients

healthy subjects without cerebrovascular disease

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

A total of 300 incident ischemic stroke patients will be recruited in the program project.

You may qualify if:

  • incident ischemic stroke patients diagnosed by CT or MRI.

You may not qualify if:

  • non ischemic stroke patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

WanFang Hospital

Taipei, Taiwan

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Buffy coat and plasma will be retained.

MeSH Terms

Conditions

Ischemic Stroke

Condition Hierarchy (Ancestors)

StrokeCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Hung-Yi Chiou

    Taipei Medical University WanFang Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

December 27, 2009

First Posted

December 29, 2009

Study Start

December 1, 2009

Primary Completion

November 1, 2010

Study Completion

November 1, 2010

Last Updated

December 3, 2010

Record last verified: 2010-12

Locations

TW(1)