Routine Screening for Eosinophilic Esophagitis in Patients Presenting With Dysphagia
1 other identifier
observational
150
1 country
2
Brief Summary
The purpose of this study is to identify the prevalence of pathologic eosinophilic esophagitis (EoE) in the cohort of adult patients who present for specialty care in the gastroenterology clinics with complaint of difficulty swallowing (dysphagia). From this, the investigators will make recommendations regarding routine screening for the diagnosis in this cohort. The prevalence of EoE in patients presenting for specialty care in the gastroenterology clinics with the complaint of dysphagia is great enough that the diagnosis should be routinely screened against in this cohort.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2006
Longer than P75 for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2006
CompletedFirst Submitted
Initial submission to the registry
December 8, 2009
CompletedFirst Posted
Study publicly available on registry
December 9, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2010
CompletedDecember 9, 2009
November 1, 2009
4 years
December 8, 2009
December 8, 2009
Conditions
Keywords
Study Arms (2)
Obstructive Dysphagia
Patients who complained of dysphagia, which had an obstructive etiology for their symptoms at the time of endoscopy (ring, mass, stricture, etc)
Non-obstructive Dysphagia
Patients whose endoscopy was normal and without any obvious etiology for their symptoms noted.
Eligibility Criteria
Adult patients over age 18, presenting to the Gastroenterology Clinic with the complaint of dysphagia
You may qualify if:
- age \> 18
- complaint of dysphagia
You may not qualify if:
- pregnancy
- age \<18
- on inhaled steroids within the last 30 days
- on systemic steroids in the last 30 days
- known diagnosis of Eosinophilic Esophagitis
- obvious obstructive etiology found at endoscopy
- increased risk of bleeding (on blood thinners or anti-platelet agents other than aspirin)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Wilford Hall Medical Center
San Antonio, Texas, 78236, United States
Brooke Army Medical Center
San Antonio, Texas, 78245, United States
Biospecimen
4 endoscopic biopsies from 5 locations: duodenum, stomach, distal esophagus, mid esophagus and proximal esophagus
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jonathan M Ricker, DO
San Antonio Uniformed Services Health Education Consortium
Central Study Contacts
Study Design
- Study Type
- observational
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- FED
Study Record Dates
First Submitted
December 8, 2009
First Posted
December 9, 2009
Study Start
January 1, 2006
Primary Completion
January 1, 2010
Study Completion
January 1, 2010
Last Updated
December 9, 2009
Record last verified: 2009-11