Auditory Neuropathy and Cochlear Implants

NCT01023932 | Completed

• 1 other identifier: NADA2009
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

The electrical stimulation generated by the Cochlear Implant (CI) may improve the neural synchrony and hence contribute to the development of auditory skills in patients with Auditory Neuropathy / Auditory Dys-synchrony (AN/AD). Goal: The goal of the research was to evaluate the auditory performance and the characteristics of the electrically evoked compound action potential (ECAP) in a group of 18 cochlear implants recipients with AN/AD.The auditory perception was evaluated by sound field thresholds and speech perception tests. To evaluate ECAP's characteristics, the threshold and amplitude of neural response together with the amplitude growth and recovery functions were evaluated at 80Hz stimulation rate.The CI was seen as an efficient resource to develop auditory skills in 94% of the AN/AD patients considered by the research. The auditory perception benefits as well as the possibility to measure the ECAP showed that the electrical stimulation could compensate the neural dys-synchrony caused by the AN/AD. However, a unique clinical procedure cannot be proposed at this point. Therefore, a careful and complete evaluation of each AN/AD patient before recommending the Cochlear Implant is advised

Conditions

Cochlear Implants; Auditory Neuropathy

Outcome Measures

Primary Outcomes (1)

• The CI was seen as an efficient resource to develop auditory skills in 94% of the AN/AD patients considered by the research.

Study Arms (1)

Auditory Neuropathy Patients

Device: Cochlear Implants

Interventions

Cochlear Implants DEVICE

Auditory Neuropathy Patients

Eligibility Criteria

• Age: 2 Years+
• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Children with auditory neuropathy who had received a cochlear implant

You may qualify if:

• All children with AN/AD who had received the cochlear implant during the research´s period.

Sponsors & Collaborators

• University of Sao Paulo: lead
• Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.: collaborator

Study Sites (1)

Bionic Ear Center

São Paulo, São Paulo, 1150000, Brazil

Location

Related Publications (1)

• de Carvalho ACM, Bevilacqua MC, Sameshima K, Filho OAC. Auditory neuropathy/Auditory dyssynchrony in children with Cochlear Implants. Braz J Otorhinolaryngol. 2011 Jul-Aug;77(4):481-487. doi: 10.1590/S1808-86942011000400012.

  PMID: 21860975 DERIVED

MeSH Terms

Conditions

Auditory neuropathy

Interventions

Cochlear Implants

Intervention Hierarchy (Ancestors)

Neural Prostheses; Implantable Neurostimulators; Electrodes, Implanted; Electrodes; Electrical Equipment and Supplies; Equipment and Supplies; Prostheses and Implants; Hearing Aids; Sensory Aids

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: December 1, 2009
• First Posted: December 2, 2009
• Study Start: September 1, 2006
• Study Completion: September 1, 2009
• Last Updated: December 2, 2009

Record last verified: 2009-12

Locations

BR (1)