The Effect of Exposure to Maternal Human Milk Odor on Physiological State of Preterms.

NCT01012505 | Unknown

• 1 other identifier: SHEBA-09-7392-AM-CTIL
• Study Type: observational
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Mammalian fetal sensory development comes in an invariant series, with the tactile/kinesthetic and chemosensory systems the earliest functioning and responsive to stimulation, implicating the importance of these foundational sensory systems for later development. Olfaction is essential for neonatal behavioral adaptation in many mammals, including humans. Experiments show that newborns recognize, and are soothed by, the smell of amniotic fluid. Provision of the mother's smell with breast pads, handkerchiefs she has worn, breast milk on a cotton ball or cotton applicator, or other means of providing odor and taste input can facilitate recognition by the infant's mother at a later time and does not appear to be detrimental to the stability of the infant. Provision of the odor and taste of the mother's milk has been shown to facilitate the infant's mouthing, sucking, arousal, and calming from irritability, especially in preparation for oral feeding. Using 24 hour monitor analysis and cortisol saliva measurements, we will provide quantitive analysis to the effect of smell.

Conditions

Health Preterm Infants With no Active Disease; Human Milk Nutrition; Incubator Stay

Study Arms (1)

20 preterm infants

20 preterm infants without active disease

Other: adding pad with maternal milk in hte incubator

Interventions

adding pad with maternal milk in hte incubator OTHER

2 days prior to intervention - recording infants data and taking saliva cortisol adding pad with maternal milk - during 2 days - recording infants data and taking saliva cortisol. stopping intervention and for other 2 days recording infants data and taking saliva cortisol

20 preterm infants

Eligibility Criteria

• Age: 7 Days - 4 Weeks
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

preterm infants at least 1 weekk of age no active disease or treatment (like respiratory support) place in incubator

You may qualify if:

• preterm infants at least 1 week of age
• no active disease or treatment (like respiratory support)
• place in incubator

You may not qualify if:

• active disease or treatment

Sponsors & Collaborators

• Sheba Medical Center: lead
• Tel Aviv University: collaborator

Study Sites (1)

Sheba medical center

Ramat Gan, 52621, Israel

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV

Study Record Dates

• First Submitted: November 11, 2009
• First Posted: November 13, 2009
• Study Start: December 1, 2009
• Last Updated: November 13, 2009

Record last verified: 2009-11

Locations

IL (1)