NCT01010594

Brief Summary

It has been questioned whether patients with type 2 diabetes who are advised to restrict their fruit consumption to two or less pieces of fruits daily have better outcomes (HbA1c, body weight, fruit intake and serum lipids) after three months compared to patients with type 2 diabetes who are advised to eat at least two pieces of fruits. To the investigators' knowledge, no randomized controlled trial has evaluated this. The investigators therefore perform a randomized controlled trial including 76 patients with type 2 diabetes to investigate this. The investigators' hypothesis is that: Type 2 diabetics who are advised to restrict their fruit consumption have the same Hba1c three months after an initially dietary treatment as type 2 diabetics who are advised not to restrict their fruit consumption.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
64

participants targeted

Target at P25-P50 for not_applicable diabetes-mellitus-type-2

Timeline
Completed

Started Nov 2009

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2009

Completed
8 days until next milestone

First Submitted

Initial submission to the registry

November 9, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 10, 2009

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2011

Completed
Last Updated

March 21, 2013

Status Verified

March 1, 2013

Enrollment Period

1.6 years

First QC Date

November 9, 2009

Last Update Submit

March 20, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in Hba1c

    three months

Secondary Outcomes (3)

  • change in bodyweight

    three months

  • change in serum lipids

    three months

  • change in fruit intake

    three months

Study Arms (2)

Fruit restricted

ACTIVE COMPARATOR

Type 2 diabetics are advised to restrict their fruit intake to two pieces or less daily.

Behavioral: dietary treatment

Fruit ad libitum

ACTIVE COMPARATOR

Type 2 diabetics are advised to eat at least two pieces of fruits daily

Behavioral: dietary treatment

Interventions

A standard dietary treatment except that they are advised to restrict their fruit intake.

Fruit restricted

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients refered from a general practitioner

You may not qualify if:

  • no Hba1c when refered
  • Hba1c lower than 5% or higher than 12%
  • patients that require a translator
  • patients with severe cardiovascular, renal or endocrine disease
  • psychiatric patients
  • pregnant patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of nutrition, Regional Hospital West Jutland

Holstebro, Holstebro, 7500, Denmark

Location

Related Publications (1)

  • Christensen AS, Viggers L, Hasselstrom K, Gregersen S. Effect of fruit restriction on glycemic control in patients with type 2 diabetes--a randomized trial. Nutr J. 2013 Mar 5;12:29. doi: 10.1186/1475-2891-12-29.

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Allan S Christensen, MHSc

    The Department of Endocrinology and Metabolism, Aarhus University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MHSc, RD

Study Record Dates

First Submitted

November 9, 2009

First Posted

November 10, 2009

Study Start

November 1, 2009

Primary Completion

June 1, 2011

Study Completion

June 1, 2011

Last Updated

March 21, 2013

Record last verified: 2013-03

Locations