NCT01004055

Brief Summary

The purpose of this study is to determine whether a bioelectric wound dressing, a silver-coated dressing, or a silver-foam dressing are effective in the treatment of wounds resulting from curettage and electrodesiccation of skin lesions.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for phase_2

Timeline
Completed

Started Jul 2008

Shorter than P25 for phase_2

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2008

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2009

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2009

Completed
26 days until next milestone

First Submitted

Initial submission to the registry

October 27, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 29, 2009

Completed
Last Updated

October 29, 2009

Status Verified

October 1, 2009

Enrollment Period

1.1 years

First QC Date

October 27, 2009

Last Update Submit

October 28, 2009

Conditions

Keywords

WoundSkin lesionAntimicrobialBioelectric

Outcome Measures

Primary Outcomes (1)

  • Wound healing over time

    July 2008-October 2009

Secondary Outcomes (1)

  • Comparing three FDA cleared products for pain reduction and incidence of infection

    July 2008-October 2009

Study Arms (3)

Procellera™ Wound Dressing

EXPERIMENTAL
Device: Procellera™ Antimicrobial Wound Dressing

ACTICOAT™

ACTIVE COMPARATOR
Drug: ACTICOAT™ Antimicrobial Barrier Dressing

Mepilex® Ag

ACTIVE COMPARATOR
Drug: Mepilex® Ag Silver Foam Dressing

Interventions

Dressing indicated for partial and full-thickness wounds. Dressing changes every 2-3 days, more frequently if needed

Also known as: PROCELLERA™, PROSIT™, Bioelectric Wound Dressing
Procellera™ Wound Dressing

Dressing changes every 2-3 days, more frequently if needed

Also known as: ACTICOAT™
ACTICOAT™

Dressing changes every 2-3 days, more frequently if needed

Also known as: Mepilex® Ag
Mepilex® Ag

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • If female, must either be not of childbearing potential or if they are of childbearing potential must have a negative urine pregnancy test
  • Wound size greater than 1x1cm
  • Wound must be ≥5 cm away from all other wounds
  • Wound size must not be diminished in size greater than 10% between enrollment in study and the prescreening
  • Participant agrees to participate in follow-up evaluation
  • Participant must be able to read and understand informed consent, and sign the informed consent

You may not qualify if:

  • Concurrent participation in another clinical trial that involves an investigational drug or device that would interfere with this study
  • Participant is to receive another topical antimicrobial agent other than the study dressing
  • Participant with sensitivity or adverse reactions to silver or zinc
  • Pregnancy or nursing an infant or child
  • Immunosuppression
  • Active or systemic infection
  • Collagen vascular disease
  • Diabetes
  • Venous stasis ulcers
  • Participant undergoing active cancer chemotherapy
  • Chronic steroid use
  • Decision impairment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Sheftel Associates Dermatology, LLC

Oro Valley, Arizona, 85755, United States

Location

Sheftel Associates Dermatology, LLC

Tucson, Arizona, 85718, United States

Location

MeSH Terms

Conditions

Wound InfectionWounds and Injuries

Interventions

Acticoat

Condition Hierarchy (Ancestors)

Infections

Study Officials

  • Scott N Sheftel, MD

    Sheftel Associates Dermatology, LLC

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

October 27, 2009

First Posted

October 29, 2009

Study Start

July 1, 2008

Primary Completion

August 1, 2009

Study Completion

October 1, 2009

Last Updated

October 29, 2009

Record last verified: 2009-10

Locations