NCT01001858

Brief Summary

The aim of the investigators study was to evaluate the effectiveness of a home programme (diagnosis and follow-up) in patients with Obstructive Sleep Apnea (OSA) syndrome treated with CPAP and to analyze the cost of this approach.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
66

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2003

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2003

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2004

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2004

Completed
4.9 years until next milestone

First Submitted

Initial submission to the registry

October 7, 2009

Completed
20 days until next milestone

First Posted

Study publicly available on registry

October 27, 2009

Completed
Last Updated

July 27, 2010

Status Verified

October 1, 2009

Enrollment Period

1.5 years

First QC Date

October 7, 2009

Last Update Submit

July 26, 2010

Conditions

Keywords

OSACPAP compliancenurse domiciliary ledsleep disease

Outcome Measures

Primary Outcomes (1)

  • Differences in compliance among the three different strategies, measured by CPAP hours of use

    six months follow-up

Secondary Outcomes (1)

  • costs of the three different strategies, including number of visits and phone calls that were necessary to improve compliance and additional diagnostic tests.

    six months follow-up

Study Arms (3)

Domiciliary group

ACTIVE COMPARATOR

In this group OSA diagnosis was performed at patient's home by mean of non-attended RP. All follow-up visits were conducted by a trained nurse in patient's home.

Other: Diagnosis and monitoring of OSA patients

Hospital Group

ACTIVE COMPARATOR

In this group diagnosis was made by in-hospital PSG. Follow-up was performed at hospital by a specialist Physician

Other: Diagnosis and monitoring of OSA patients

Mixed Group

ACTIVE COMPARATOR

In this group diagnosis was made by home RP, and follow-up at hospital

Other: Diagnosis and monitoring of OSA patients

Interventions

The difference between the three strategies is given by the method used for OSA diagnosis (domiciliary RP or hospital PSG) and the type of monitoring carried out after initiating CPAP treatment (by physician at hospital or by a trained nurse in patient's home)

Also known as: Domiciliary group: group A, Hospital group: group B, Mixed Group: groupC
Domiciliary groupHospital GroupMixed Group

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with high probability of OSA, defined by two or more of :
  • daytime sleepiness
  • snoring
  • recognized apnoeic episodes
  • associating obesity and / or hypertension

You may not qualify if:

  • Patients with impaired lung function ( overlap syndrome, obesity-hypoventilation syndrome, restrictive disorders), associated pathology (psychiatric disorder, periodic limb movements, dyssomnias or other parasomnias)
  • Patients treated with CPAP

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital San Juan de Alicante

San Juan, Alicante, 03550, Spain

Location

Related Publications (1)

  • Andreu AL, Chiner E, Sancho-Chust JN, Pastor E, Llombart M, Gomez-Merino E, Senent C, Barbe F. Effect of an ambulatory diagnostic and treatment programme in patients with sleep apnoea. Eur Respir J. 2012 Feb;39(2):305-12. doi: 10.1183/09031936.00013311. Epub 2011 Jun 30.

MeSH Terms

Conditions

Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Study Officials

  • Eusebi Chiner Vives, MD

    Jefe de Sección de Neumología del Hospital San Juan de Alicante. España

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

October 7, 2009

First Posted

October 27, 2009

Study Start

June 1, 2003

Primary Completion

December 1, 2004

Study Completion

December 1, 2004

Last Updated

July 27, 2010

Record last verified: 2009-10

Locations