Pilot Study of Text Message Reminders to Improve HIV Medication Adherence in Botswana
A Pilot Study of Cellular Phone Text Message Reminders to Improve HIV Medication Adherence at Independence Surgery Clinic Gaborone, Botswana
2 other identifiers
interventional
128
1 country
1
Brief Summary
While medication adherence is critical to successful treatment of HIV, there are few studies of interventions demonstrating improvements in adherence. This may be a particular challenge in the developing world, which has a larger burden of HIV but fewer resources than industrialized countries. The investigators propose a randomized controlled trial of cellular phone text message reminders to improve medication adherence. Our pilot study will be set in a large HIV clinic in Gaborone, Botswana, where Penn researchers have collaborated on research projects in the past. The primary study outcome will be antiretroviral medication adherence.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable hiv-infections
Started Jun 2008
Shorter than P25 for not_applicable hiv-infections
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2009
CompletedFirst Submitted
Initial submission to the registry
October 23, 2009
CompletedFirst Posted
Study publicly available on registry
October 27, 2009
CompletedSeptember 17, 2015
June 1, 2010
1.2 years
October 23, 2009
September 16, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
HIV medication adherence
Monthly
Interventions
We will use cellular text messages to remind patients of impending drug prescription refills and scheduled visits to their healthcare provider.
Eligibility Criteria
You may qualify if:
- HIV infected
- years of age or older
You may not qualify if:
- Subjects who do not intend to have continuous follow-up care and monthly medication refills at Independence Surgery for at least the next six months
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Independence Surgery
Gaborone, Botswana
Related Publications (1)
Reid MJ, Dhar SI, Cary M, Liang P, Thompson J, Gabaitiri L, Steele K, Mayisela S, Dickinson D, Friedman H, Linkin DR, Steenhoff AP. Opinions and attitudes of participants in a randomized controlled trial examining the efficacy of SMS reminders to enhance antiretroviral adherence: a cross-sectional survey. J Acquir Immune Defic Syndr. 2014 Feb 1;65(2):e86-8. doi: 10.1097/QAI.0b013e3182a9c72b. No abstract available.
PMID: 24442231RESULT
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Darren Linkin, MD
University of Pennsylvania
- PRINCIPAL INVESTIGATOR
Harvey Friedman, MD
University of Pennsylvania
- STUDY DIRECTOR
James Thompson, MBA
Wharton Business School, UPenn
- STUDY DIRECTOR
Andrew Steenhoff
University of Pennsylvania
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 23, 2009
First Posted
October 27, 2009
Study Start
June 1, 2008
Primary Completion
August 1, 2009
Study Completion
August 1, 2009
Last Updated
September 17, 2015
Record last verified: 2010-06