Risk Reduction for Drug Use and Sexual Revictimization

NCT00998153 | Completed DMC

• 1 other identifier: K23DA018686
• Study Type: interventional
• Target: 135
• Locations: 1 country
• Sites: 1

Brief Summary

The investigator proposes to evaluate Risk Reduction through Family Therapy (RRFT), which integrates: 1) an ecologically-based intervention for treatment of substance abuse behaviors in high risk adolescents, 2) exposure-based cognitive-behavioral therapy for sexually assaulted youth, and 3) psychoeducation strategies for prevention of risky sexual behaviors and revictimization. The principal purpose of this research proposal is to evaluate the efficacy of RRFT in reducing the risk of drug abuse and other risky behaviors, PTSD, and revictimization among adolescents who have been sexually assaulted. The Research Plan will be conducted based on Stage 1a and Stage 1b from NIDA's Behavioral Therapies Development Program as described in Rounsaville, Carroll, \& Onken (2001). The final phase of the research will involve conducting a pilot randomized controlled trial of RRFT in a sample of adolescents, comparing primary outcome measures of youth receiving RRFT to youth receiving usual care in the community. Participants will be adolescents (12-17 years) who have experienced a sexual assault. Assessment of substance use and other risk behaviors, trauma-related psychopathology, and incidents of revictimization will be collected at pre- and post- treatment, as well as 6-week and 3-month follow-ups. Hierarchical Linear Modeling will be the primary method used to test study hypotheses. Development and evaluation of the proposed intervention will have significant implications for addressing public health problems in adolescent substance abuse and related high risk behaviors.

Conditions

Risk Reduction Through Family Therapy; Usual Care

Keywords

substance use; PTSD; risky behaviors; revictimization

Outcome Measures

Primary Outcomes (1)

• Time Line Follow Back and urine screen

  Pre and post-treatment, 3 and 6 month follow-ups

Secondary Outcomes (3)

• YRBS

  Pre and post-treatment, 3 and 6 month follow-ups

• FES

  Pre and post-treatment, 3 and 6 month follow-ups

• UCLA PTSD Reaction Index

  Pre, post, and 3 and 6 month follow-up

Study Arms (2)

1

EXPERIMENTAL

RRFT

Behavioral: Risk Reduction through Family Therapy

2

ACTIVE COMPARATOR

Usual care

Behavioral: Risk Reduction through Family Therapy

Interventions

Risk Reduction through Family Therapy BEHAVIORAL

Component based intervention based on existing empirically supported treatments

Also known as: RRFT

1; 2

Eligibility Criteria

• Age: 12 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• memorable sexual assault

You may not qualify if:

• active psychosis
• active suicidality

Sponsors & Collaborators

• Medical University of South Carolina: lead
• National Institute on Drug Abuse (NIDA): collaborator

Study Sites (1)

National Crime Victims Research and Treatment Center

Charleston, South Carolina, 29425, United States

Location

Related Publications (1)

• Danielson CK, McCart MR, Walsh K, de Arellano MA, White D, Resnick HS. Reducing substance use risk and mental health problems among sexually assaulted adolescents: a pilot randomized controlled trial. J Fam Psychol. 2012 Aug;26(4):628-35. doi: 10.1037/a0028862. Epub 2012 Jun 11.

  PMID: 22686269 DERIVED

MeSH Terms

Conditions

Substance-Related Disorders; Stress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders; Stress Disorders, Traumatic; Trauma and Stressor Related Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 19, 2009
• First Posted: October 20, 2009
• Study Start: July 1, 2006
• Primary Completion: June 30, 2011
• Study Completion: June 30, 2012
• Last Updated: June 18, 2018

Record last verified: 2018-05

Locations

US (1)