NCT00993330|TerminatedDMC
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Sponsor study identifier
observational
96
1 country
1
Study Start
May 2009
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
September 2010
Actual (reported)Study Completion
December 2010
Actual (reported)The macular pigment (MP) in humans consists of the yellow, blue-absorbing carotenoids lutein and zeaxanthin, which are contained in vegetables and fruits. The highest concentrations of lutein and zeaxanthin are found in the fovea. Since light entering the eye passes through the MP before reaching the photo receptors it absorbs a significant portion of short-wavelength light. There is evidence that these absorbing properties of the MP as well as the ability of inactivating highly reactive oxygen species are protective for the retina. Measurement of macular pigment is difficult and the investigators have recently proposed a way of measuring macular pigment optical density (MPOD) based on optical reflectometry. There is increased interest in these measurements in the recent years, because a number of studies has provided evidence that low fruit and vegetable consumption increases the risk of age related macular degeneration (AMD). The present study investigates MP optical density (OD) in healthy volunteers and is used to form a database. Furthermore the nutritional habits and the influence on MP density will be evaluated.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2010
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 2009
Date type not reportedThis date has not been verified as actual or estimated.
October 9, 2009
Actual (reported)October 12, 2009
Actual (reported)September 2010
Actual (reported)December 2010
Actual (reported)MPOD as measured with optical reflectometry
1 year
20 healthy subjects between 18 and 40 years
20 healthy subjects between 41 and 50 years
20 healthy subjects between 51 and 60 years
20 healthy subjects between 61 and 70 years
20 healthy subjects between 71 and 80 years
20 healthy subjects between 81 and 90 years
Healthy subjects
Department of Clinical Pharmacology, Medical University of Vienna
Vienna, 1090, Austria
Gerhard Garhofer, MD
Medical University of Vienna
96 participants (actual enrollment reported by the registry).
First Submitted
October 9, 2009
First Posted
October 12, 2009
Study Start
May 2009
Date type not reportedThis date has not been verified as actual or estimated.
Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation for Two More Years (LUTEGA 2)
Contact the study team to confirm eligibility.
Primary Completion
September 2010
Actual (reported)Study Completion
December 2010
Actual (reported)Last Updated
November 14, 2014
Record last verified: 2014-11
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Source: ClinicalTrials.gov.
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