NCT00986492

Brief Summary

Evidence that shortened period of sleep could be a risk factor for weight gain and obesity has grown over the past decade. Concurrent with the obesity epidemic, numerous studies have reported a parallel epidemic of chronic sleep deprivation. Sleep is important in maintaining energy balance (i.e. acute sleep deprivation impact the normal secretion of ghrelin and decreases leptin plasma levels). Surprisingly, in humans, there is no direct evidence that a shortened night has direct effect on energy metabolism during the following day. This study is set up to determine whether a partial sleep deprivation night has an impact on appetite and food energy intake and, concomitantly, on physical activity, during the following day.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Apr 2009

Shorter than P25 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2009

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2009

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

September 24, 2009

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 30, 2009

Completed
Last Updated

September 30, 2009

Status Verified

September 1, 2009

Enrollment Period

2 months

First QC Date

September 24, 2009

Last Update Submit

September 29, 2009

Conditions

Healthy

Keywords

Sleep deprivationFood intakeMotor activityNormal, healthy subjects

Outcome Measures

Primary Outcomes (1)

  • Daily food intake

    24h

Eligibility Criteria

Age18 Years - 30 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Healthy normal subjects

You may qualify if:

  • male
  • age between 18 and 30
  • healthy
  • non smoker
  • less than 5 hour of sport per week
  • BMI between 20 and 25 kg/m/m

You may not qualify if:

  • eating disorders,
  • dieting or fasting
  • restrained (score \>9), disinhibited (score \>11) or hungry subjects (score \>9), according to the Three-Factor Eating Questionnaire general healthiness,
  • food-snacking (more than twice a day),

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Brondel L, Romer MA, Nougues PM, Touyarou P, Davenne D. Acute partial sleep deprivation increases food intake in healthy men. Am J Clin Nutr. 2010 Jun;91(6):1550-9. doi: 10.3945/ajcn.2009.28523. Epub 2010 Mar 31.

    PMID: 20357041DERIVED

MeSH Terms

Conditions

Sleep DeprivationMotor Activity

Condition Hierarchy (Ancestors)

DyssomniasSleep Wake DisordersNervous System DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsMental DisordersBehavior

Study Officials

  • Pierre Denise, MD, PhD

    University Hospital, Caen

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 24, 2009

First Posted

September 30, 2009

Study Start

April 1, 2009

Primary Completion

June 1, 2009

Study Completion

June 1, 2009

Last Updated

September 30, 2009

Record last verified: 2009-09