Restasis for Treatment of Brittle Nails

You may not qualify if:

• have a history of surgery of the affected fingernails
• are chronic nail biters
• are pregnant, nursing, or planning pregnancy prior to study enrollment
• have a disturbance of the shape of the affected fingernails (e.g., due to malformation of the underlying bone) that would interfere with the investigator's ability to evaluate photographs or nail changes
• have onycholysis (lifting of the nail plate off the nail bed) of the affected fingernails
• have signs of a fungal or bacterial infection of the affected fingernails
• have a history of psoriasis or lichen planus involving any nail, or active contact dermatitis involving the affected fingernails
• have used any topical cosmetics or medicated products on the affected nails within 2 weeks of baseline visit
• have received oral antifungal treatment within 3 months of baseline visit
• have a known or suspected history of a genetic condition affecting the nails (e.g., Darier's disease, nail-patella syndrome, tuberous sclerosis)
• have used any investigational drug within the previous 1 month or 5 half-lives of the investigational agent, whichever is longer, or 3 months for any biologic of unknown half-life
• are known or suspected to have had a substance abuse (drug or alcohol) problem within the previous 3 years
• is unlikely to comply with the study protocol and prescribed treatment or is unsuitable for any other reason in the opinion of the investigator
• chronic liver, heart, kidney, or (untreated) thyroid disease
• have current signs or symptoms of severe, progressive, or uncontrolled renal, hepatic, hematologic, gastrointestinal, endocrine, pulmonary, cardiac, neurologic, or cerebral disease
• +3 more criteria