NCT00983450

Brief Summary

The study will include 20 subjects who will be randomly divided to two groups: a ten person group being the study group and a ten person group acting as a control group (each group will include a similar number of females and males as the other group). In addition, the physiotherapy treatments at the rehabilitation center, the study group will gain an intervention consisting of 12 therapy sessions, administered for 12 consecutive days (apart of weekends). The intervention will include 6 minutes of watching a movie clip alternately showing a healthy man and a healthy woman at their sixties, walking while being filmed from various angles. Immediately after watching, the subject will perform 6 minutes of walking, under the experimenters supervision, but without his or hers intervention. Immediately following the walking, the whole procedure will be repeated (watching a clip and walking). The control group will undergo 12 treatments of the same nature, but will watch the movie clip shown backwards, so that the people filmed will seem to walk backwards (it was established that watching a reversed action does not activate the MNS system activated by a regular execution of the activity \[Celnik et al., 2008\]), followed by 6 minutes of walking under the experimenters supervision, then watching the movie again and walking again. The person performing the examinations will be blinded as to the division of the subjects to the study group and the control group. After performing the previously noted examinations needed to participate in the research, the subjects found fit will be examined before the beginning of the intervention, at its end and then three months after its conclusion. The examinations will include smart step and walking parameters.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for phase_2 stroke

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 6, 2009

Completed
18 days until next milestone

First Posted

Study publicly available on registry

September 24, 2009

Completed
7 days until next milestone

Study Start

First participant enrolled

October 1, 2009

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2010

Completed
Last Updated

June 3, 2010

Status Verified

September 1, 2009

Enrollment Period

1.2 years

First QC Date

September 6, 2009

Last Update Submit

June 2, 2010

Conditions

Outcome Measures

Primary Outcomes (1)

  • Smart step examination- Average weight on the hind foot and fore foot. Cycle - time (in seconds) from one initial contact to the other (on the same foot). Stance and swing average percentage of one walking cycle, Cadence

    before the beginning of the intervention, at its end and then three months after its conclusion.

Secondary Outcomes (1)

  • 2. Two min. walking test. 3. Ten meter walking test. 4. An ABC questioner to determine the personal confidence in regards to walking.

    before the beginning of the intervention, at its end and then three months after its conclusion.

Study Arms (2)

study group

EXPERIMENTAL

People after a first ischemic or hemorrhagic stroke, up to 60 days following the event.

Other: watching a normal walking clip

CONTROL

EXPERIMENTAL

People after a first ischemic or hemorrhagic stroke, up to 60 days following the event.

Other: watching walk backward clip

Interventions

the study group will gain an intervention consisting of 12 therapy sessions, administered for 12 consecutive days (apart of weekends). The intervention will include 6 minutes of watching a movie clip alternately showing a healthy man and a healthy woman at their sixties, walking while being filmed from various angles. Immediately after watching, the subject will perform 6 minutes of walking, under the experimenters supervision, but without his or hers intervention. Immediately following the walking, the whole procedure will be repeated (watching a clip and walking).

study group

The control group will undergo 12 treatments of the same nature, but will watch the movie clip shown backwards, so that the people filmed will seem to walk backwards (it was established that watching a reversed action does not activate the MNS system activated by a regular execution of the activity \[Celnik et al., 2008\]), followed by 6 minutes of walking under the experimenters supervision, then watching the movie again and walking again.

CONTROL

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • People after a first ischemic or hemorrhagic stroke, up to 60 days following the event.
  • A FAC (Functional Ambulation Category) score test result of 2 or 3, in order to ensure basic mobility, even if still requiring supervision.
  • A NIHSS (National Institutes of Health Stroke Scale) score of 3 to 18.
  • Patients suffering from the following will not be part of the study:
  • Significant neglect (a BIT score under 129 in the conventional tests).
  • Hemianopsy as determined upon a clinical examination by a rehabilitation physician.
  • Clarity of vision problem, determined upon an SC based examination.
  • Significant cognitive decline (a Mini mental test score of under 24).
  • Aphasia which prevents understanding the signing a Helsinki form.

You may not qualify if:

  • Patients participating in concurrent researches will not participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hadassah University Hospital

Jerusalem, Israel

Location

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Zeev meiner, M.D

    Hadassah Medical Organization

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Zeev Meiner, M.D.

CONTACT

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 6, 2009

First Posted

September 24, 2009

Study Start

October 1, 2009

Primary Completion

December 1, 2010

Last Updated

June 3, 2010

Record last verified: 2009-09

Locations