The Effects of Pistacia Mutica on De Novo Dental Plaque Formation, Gingival Inflammation and Oral Microorganisms
1 other identifier
interventional
25
1 country
1
Brief Summary
Dental plaque is a well known etiologic factor for gingivitis. Recently, herbal extracts are a matter of scientific interest to inhibit plaque accumulation on teeth. The purpose of this study was to evaluate the effects of pistacia Mutica (PM) mouth wash on de novo dental plaque plaque formation, gingival inflammation indices and oral microorganisms.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for phase_2
Started May 2008
Shorter than P25 for phase_2
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2009
CompletedFirst Submitted
Initial submission to the registry
September 8, 2009
CompletedFirst Posted
Study publicly available on registry
September 9, 2009
CompletedSeptember 9, 2009
February 1, 2007
September 8, 2009
September 8, 2009
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
The effects of pistacia Mutica extract (PM) on de novo plaque formation.
In a 4 days experimental periods followed by a 10 days wash-out periods.
Secondary Outcomes (1)
staining effects of pistacia Mutica extract in comparison to placebo or Chlorhexidine
In a 4 days experimental periods followed by a 10 days wash-out periods
Study Arms (3)
pistacia Mutica
EXPERIMENTALThe subjects were asked to use a mouthwash containing pistacia Mutica extract twice a day for 4 days.
placebo
PLACEBO COMPARATORThe subjects were asked to use a mouthwash containing Placebo twice a day for 4 days.
Chlorhexidine
ACTIVE COMPARATORThe subjects were asked to use a mouthwash containing Chlorhexidine twice a day for 4 days.
Interventions
The subjects were asked to use a mouthwash containing pistacia Mutica extract twice a day for 4 days.
The subjects were asked to use a mouthwash containing Chlorhexidine twice a day for 4 days.
Eligibility Criteria
You may qualify if:
- had merely gingivitis (pocket depth≤3 mm, no attachment loss)
- without any fixed or removable oral appliances
You may not qualify if:
- Individuals who had a history of any relevant systemic diseases
- Individuals who had a history of any drug usage
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Drug Applied Science Center, tabriz Univ. of Medical Sciences
Tabriz, East Azerbaijan Province, Iran
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Reza Pourabbas, DDS,MSD
Tabriz University of Medical Sciences
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
September 8, 2009
First Posted
September 9, 2009
Study Start
May 1, 2008
Study Completion
May 1, 2009
Last Updated
September 9, 2009
Record last verified: 2007-02