NCT00972088

Brief Summary

To show that prevalence of inflammation of the small bowel in patients with anorectal disease is under-diagnosed based on colonoscopy ileoscopy alone.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
26

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2008

Typical duration for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2008

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

September 2, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 4, 2009

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2011

Completed
2.1 years until next milestone

Results Posted

Study results publicly available

June 24, 2013

Completed
Last Updated

June 24, 2013

Status Verified

May 1, 2013

Enrollment Period

2.8 years

First QC Date

September 2, 2009

Results QC Date

February 4, 2012

Last Update Submit

May 15, 2013

Conditions

Keywords

inflammation of the small bowel

Outcome Measures

Primary Outcomes (1)

  • Prevalence of Inflammation as Diagnosed by Capsule Endoscopy

    The capsule endoscopy findings were carefully examined by specialists in the field. findings such as erosions, edema, erythema and ulceration in significant areas of the intestine led to the clinical diagnosis of crohn's disease. all together 6 patients were diagnosed as suffering from crohn's disease.

    up to 7 days

Study Arms (1)

capsule endoscopy

OTHER

patients eligible according to inclusion criteria who underwent a capsule endoscopy

Device: capsule endoscopy

Interventions

The disposable, ingestible PillCam® SB2 Capsule acquires the video images during natural propulsion through the digestive system. The Capsule transmits the acquired images via digital radio frequency communication channel to the Given® Data Recorder unit located outside the body.

capsule endoscopy

Eligibility Criteria

Age10 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients between the ages of 10 - 80
  • Patients with anorectal abscess of anorectal fistula
  • Patient is male or female
  • Within three months prior to enrollment, patient has normal test results for at least one of the following tests:
  • Colonoscopy with Ileoscopy, and/or
  • Colonoscopy with small bowel series, and/or
  • Colonoscopy with CT enterography
  • Within three months prior to enrollment patient has the following lab tests: Blood count, sedimentation rate, CRP. IBD serology is optional.
  • Sign informed consent

You may not qualify if:

  • Can not sign informed consent
  • Contraindications to colonoscopy ileoscopy or capsule endoscopy
  • History of established IBD

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Assaf Harofeh Medical Center

Tel Aviv, Zrifin, 70300, Israel

Location

Rambam Medical Center

Haifa, 31096, Israel

Location

Bikur Cholim Hospital

Jerusalem, 91004, Israel

Location

MeSH Terms

Conditions

Inflammatory Bowel Diseases

Interventions

Capsule Endoscopy

Condition Hierarchy (Ancestors)

GastroenteritisGastrointestinal DiseasesDigestive System DiseasesIntestinal Diseases

Intervention Hierarchy (Ancestors)

Endoscopy, GastrointestinalEndoscopy, Digestive SystemEndoscopyDiagnostic Techniques, SurgicalDiagnostic Techniques and ProceduresDiagnosis

Results Point of Contact

Title
samuel n adler md, director of clinical trial
Organization
bikur holim hospital

Study Officials

  • Samuel Adler, Prof.

    Bikur Cholim Hospital, Jerusalem

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. Samuel N. Adler, MD

Study Record Dates

First Submitted

September 2, 2009

First Posted

September 4, 2009

Study Start

August 1, 2008

Primary Completion

June 1, 2011

Study Completion

June 1, 2011

Last Updated

June 24, 2013

Results First Posted

June 24, 2013

Record last verified: 2013-05

Locations