Correlation of Particulate Matter and Heme Oxygenase-1 Protein Activity in Asthmatic Children by Induced Sputum Analysis.
1 other identifier
observational
100
1 country
1
Brief Summary
Samples of sputum from asthmatic children, between 5-17 years, will be collected during two years of the study period to perform tests Particle Size Distribution (PSD) and Shape Analysis (SA) of the particulate matter in the sputum and a biochemical reaction to evaluate the activity of Heme Oxygenase-1 protein in sputum cell supernatants. Each child will perform Pulmonary Function Testing (PFT) and Induced Sputum (IS) as a routine part of diagnosis of asthma. Parents will be asked to complete a questionnaire including questions on their child's respiratory symptoms in the last 12 months as well as socioeconomic factors. Parents will be asked to give informed written consent for their child's participation in the study.
Trial Health
Trial Health Score
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participants targeted
Target at P50-P75 for all trials
1 active site
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Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 29, 2009
CompletedFirst Posted
Study publicly available on registry
September 1, 2009
CompletedStudy Start
First participant enrolled
October 1, 2009
CompletedNovember 25, 2009
November 1, 2009
August 29, 2009
November 21, 2009
Conditions
Eligibility Criteria
Children, between 5-17 years, performing a routine diagnosis of asthma in Tel Aviv Sourasky Medical Center
You may qualify if:
- All children, between 5-17 years, performing a routine diagnosis of asthma in Tel Aviv Sourasky Medical Center that there parents gave informed written consent for their child's participation in the study.
You may not qualify if:
- None.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Pulmonary Laboratory of Tel Aviv Sourasky Medical Center
Tel Aviv, Israel
Biospecimen
Samples of indused sputum
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- ECOLOGIC OR COMMUNITY
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER GOV
Study Record Dates
First Submitted
August 29, 2009
First Posted
September 1, 2009
Study Start
October 1, 2009
Last Updated
November 25, 2009
Record last verified: 2009-11