A Study of Atherosclerosis in Patients After Radiation Treatment for Breast Cancer
ABCART
Pilot Study "A Study of Atherosclerosis in Patients After Radiation Treatment for Breast Cancer"
1 other identifier
observational
20
1 country
1
Brief Summary
The purpose of this study is to compare plaque burden in the coronary and carotid arteries 5 years after adjuvant radiotherapy in women with right sided breast cancer vs left sided breast cancer.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Aug 2005
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2005
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2007
CompletedFirst Submitted
Initial submission to the registry
August 13, 2009
CompletedFirst Posted
Study publicly available on registry
August 17, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2014
CompletedResults Posted
Study results publicly available
November 27, 2023
CompletedNovember 27, 2023
February 1, 2023
1.7 years
August 13, 2009
January 27, 2016
February 17, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Number of Participants Analyzed for Coronary Calcium Burden by AGS
Number of participants who received a coronary calcium scan.
Year 5 Post-Initiation of Radiotherapy
Study Arms (2)
cardiac counseling
10 left sided breast cancer patients 10 right sided breast cancer patients
coronary artery evaluation
10 left sided breast cancer 10 right sided breast cancer
Eligibility Criteria
breast cancer patients after radiation treatment
You may qualify if:
- women dx with ductal carcinoma in situ or breast cancer, stage 0 to stage IIIc, who received conservative surgery and radiotherapy at least 5 years ago
- less than or equal to age 60
You may not qualify if:
- hx of coronary disease prior to tx of ductal carcinoma in situ or breast cancer
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Winthrop University Hospital
Mineola, New York, 11501, United States
Related Publications (1)
Chang M, Suh J, Kirtani V, Dobrescu A, Haas J, Zeldis S, Shayani S, Hindenburg AA. Coronary Calcium Scanning in Patients after Adjuvant Radiation for Early Breast Cancer and Ductal Carcinoma In situ. Front Oncol. 2013 Sep 25;3:253. doi: 10.3389/fonc.2013.00253. eCollection 2013.
PMID: 24093087BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Results Point of Contact
- Title
- Dr. Alexander Hindenburg
- Organization
- Winthrop-University Hospital, Division of Hematology and Oncology
Study Officials
- PRINCIPAL INVESTIGATOR
Alexander Hindenburg, MD
Winthrop University Hospital
Publication Agreements
- PI is Sponsor Employee
- Yes
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 13, 2009
First Posted
August 17, 2009
Study Start
August 1, 2005
Primary Completion
May 1, 2007
Study Completion
January 1, 2014
Last Updated
November 27, 2023
Results First Posted
November 27, 2023
Record last verified: 2023-02