NCT00960206

Brief Summary

The purpose of the Post Approval Study of the ABC and Trident® systems is to continue to demonstrate the safety and efficacy of the alumina-on-alumina bearing surfaces combined with the appropriate shell in a cementless application.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
413

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2003

Longer than P75 for not_applicable

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2003

Completed
6.4 years until next milestone

First Submitted

Initial submission to the registry

August 5, 2009

Completed
12 days until next milestone

First Posted

Study publicly available on registry

August 17, 2009

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2010

Completed
3.9 years until next milestone

Results Posted

Study results publicly available

August 15, 2014

Completed
Last Updated

February 3, 2017

Status Verified

December 1, 2016

Enrollment Period

7.6 years

First QC Date

August 5, 2009

Results QC Date

June 7, 2013

Last Update Submit

December 8, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Component Revision and Complications

    The number of hips in which the study device was removed and replaced with a new component/s is listed. Complications (adverse events) are listed in the adverse event section.

    10 years

Secondary Outcomes (3)

  • Harris Hip Score

    3-5 and 10 Years

  • Radiographic Evaluation

    3-5 and 10 years

  • Hip Follow-Up Questionnaire

    6-10 years

Study Arms (3)

Trident®System

EXPERIMENTAL

Trident® Ceramic Insert/Trident® AD HA Acetabular Shell

Device: Trident® Ceramic Insert/Trident® AD HA Acetabular Shell

ABC System

EXPERIMENTAL

Alumina Insert/PSL® Microstructured Acetabular Shell or Secur-Fit® HA PSL® Acetabular Shell

Device: Alumina Insert/PSL® Microstructured Acetabular Shell or Secur-Fit® HA PSL® Acetabular Shell

Control

ACTIVE COMPARATOR

OmniFit® Series II Insert/OmniFit® PSL® Microstructured Acetabular Shell

Device: OmniFit® Series II Insert/OmniFit® PSL® Microstructured Acetabular Shell

Interventions

Trident® Ceramic Insert/Trident® AD HA Acetabular Shell

Trident®System

Alumina Insert/PSL® Microstructured Acetabular Shell or Secur-Fit® HA PSL® Acetabular Shell

ABC System

OmniFit® Series II Insert/OmniFit® PSL® Microstructured Acetabular Shell

Control

Eligibility Criteria

Age21 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • The individual has signed a Patient Informed Consent (PIC), specific to this study, and approved by the Institutional Review Board (IRB).
  • The individual is between the ages of 21 and 75 years.
  • The individual is not classified as morbidly obese.
  • The individual clinically qualifies for total hip arthroplastic surgery based on physical examination and medical history.
  • The individual is diagnosed with a primary diagnosis of Non-Inflammatory Degenerative Joint Disease (osteoarthritis, traumatic arthritis, avascular necrosis, slipped capital epiphysis, pelvic fracture, femoral fracture, failed fracture fixation or diastrophic variant).
  • The individual does not have an active infection within the affected hip joint.
  • The individual has not had a previous total hip replacement or hip fusion to the affected hip joint.
  • The individual is physically and mentally willing and able to comply with postoperative scheduled clinical and radiographic evaluations and rehabilitation (i.e., not currently being treated for a psychiatric disorder, senile dementia, Alzheimer's disease, presence of alcohol or substance abuse).
  • The individual does not have a neuromuscular or neurosensory deficiency that limits the ability to evaluate the safety and effectiveness of the device.
  • The individual does not have a diagnosed systemic disease that would affect the subject's welfare or overall outcome of the study (i.e., moderate to severe osteoporosis, Paget's disease, renal osteodystrophy), is not immunologically suppressed, nor receiving steroids in excess of physiologic dose requirements.
  • The individual is skeletally mature.
  • The individual is not pregnant.
  • The individual is not a prisoner.
  • The individual has no plans to relocate to another geographic area before the completion of the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Orthopaedic Surgery Associates

Boca Raton, Florida, 33435, United States

Location

Emory Univeristy

Atlanta, Georgia, 30329, United States

Location

Indiana University

Indianapolis, Indiana, 46202, United States

Location

New England Baptist Hospital

Boston, Massachusetts, 02120, United States

Location

Toledo Joint Replacement and Orthopedic Center

Toledo, Ohio, 43623, United States

Location

Greater Pittsburgh Orthopaedics Assoc.

Moon Township, Pennsylvania, 15108, United States

Location

Results Point of Contact

Title
Director of Clinical Research
Organization
Stryker Orthopaedics

Study Officials

  • William Capello, MD

    Indiana University School of Medicine

    STUDY CHAIR
  • Benjamin Bierbaum, MD

    New England Baptist Hospital

    PRINCIPAL INVESTIGATOR
  • James D'Antonio, MD

    Greater Pittsburgh Orthopaedic Associates

    STUDY CHAIR
  • James Roberson, MD

    Emory Orthopaedics Center

    PRINCIPAL INVESTIGATOR
  • Scott Siverhus, MD

    Toledo Joint Replacement and Orthopedic Center

    PRINCIPAL INVESTIGATOR
  • Robert Zann, MD

    Orthopaedic Surgery Associates

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 5, 2009

First Posted

August 17, 2009

Study Start

March 1, 2003

Primary Completion

October 1, 2010

Study Completion

October 1, 2010

Last Updated

February 3, 2017

Results First Posted

August 15, 2014

Record last verified: 2016-12

Locations