NCT00954083

Brief Summary

Thirty two children age 2-6 years are recruited into the study and the randomization will be stratified for chronological age and symptom severity into 2 main groups, intervention and control. The intervention group will receive an additional target treatment of DIR/Floortime parent training intervention, while the control group will continue on their routine care for 3 months. Hypothesis: Children in the intervention group show much improvement in climbing the developmental "ladder" and declining in the autistic behaviors.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2007

Typical duration for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2007

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2008

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2009

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

August 4, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 6, 2009

Completed
Last Updated

August 6, 2009

Status Verified

August 1, 2009

Enrollment Period

1.3 years

First QC Date

August 4, 2009

Last Update Submit

August 5, 2009

Conditions

Outcome Measures

Primary Outcomes (1)

  • The Functional Emotional Assessment Scale (FEAS) Ratings (the child part)

    at the beginning of the first session and at the 3 months follow up

Secondary Outcomes (1)

  • The Childhood Autism Rating Scale (CARS) Clinical rating of the children (6 point scale related to Greenspan's six Functional Development Level -FDL) Satisfaction of the effectiveness of the intervention of their child (Six-point Likert scale)

    at the beginning of the first session and the 3 months follow up

Study Arms (2)

DIR/Floortime intervention

EXPERIMENTAL

1=DIR/Floortime intervention

Behavioral: DIR/Floortime

routine care

ACTIVE COMPARATOR

2=routine care

Behavioral: Routine care

Interventions

DIR/FloortimeBEHAVIORAL

Developmental, Individual-Difference, Relationship-Bases (DIR) focus more on relationship, social skills, and meaningful, spontaneous use of language and communication and integrated understand of human development

DIR/Floortime intervention
Routine careBEHAVIORAL

Routine care

routine care

Eligibility Criteria

Age2 Years - 6 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • clinical criteria for Autistic Disorders according to DSM IV
  • child is 2 - 6 years of age

You may not qualify if:

  • children with additional medical diagnosis (e.g., genetic syndromes, diagnosed hearing impairment, diagnosed visual impairment or seizures)
  • children who are geographically inaccessible for follow-up visits
  • their parents are not literate or known chronic psychiatric or physical illness in the parents

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Autism Spectrum Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, PervasiveNeurodevelopmental DisordersMental Disorders

Study Officials

  • Kingkaew Pajareya, MD

    Rehabilitation Medicine, Siriraj Hospital, Bangkok, Thailand

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 4, 2009

First Posted

August 6, 2009

Study Start

June 1, 2007

Primary Completion

October 1, 2008

Study Completion

April 1, 2009

Last Updated

August 6, 2009

Record last verified: 2009-08