Effects of White Wine vs. Tea Intake During and an Alcoholic Digestive Following a High Fat, High Calorie Cheese Fondue Meal on Gastric Emptying and Abdominal Symptoms in Healthy Volunteers

NCT00943696 | Completed Phase 4

• 1 other identifier: Fonduestudie_EKGs
• Study Type: interventional
• Target: 12
• Locations: 1 country
• Sites: 1

Brief Summary

Tradition holds that the intake of different drinks with a meal has an important influence on the digestion of food and postprandial symptoms such as fullness, bloating and satiety; however this assumption have never been subjected to controlled study A classic example is the Swiss cheese fondue. The intake of white wine, tea and cherry schnapps (Kirsch) are often attributed either positive or negative effects on the gastrointestinal tract. In this study the effect of white wine vs. tea intake during and an alcoholic digestive following a high fat, high calorie Swiss fondue meal on gastric emptying and visceral perception will be investigated using a randomized, controlled study design. The fondue will be labeled with non-radioactive 13C octanoate for assessment of gastric emptying by breath-test.

Conditions

Healthy Participants

Outcome Measures

Primary Outcomes (1)

• Effect of white wine vs. tea on gastric emptying

  4 hours

Interventions

Ingestion of white wine vs. tea during and an alco DIETARY_SUPPLEMENT

4 x 50ml glasses of white wine (12% alcohol) or tea will be taken according to a randomization scheme After the meal 1 x 20ml of Kirsch (40% alcohol) or tea will be taken

Eligibility Criteria

• Age: 19 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Body Mass Index: 19-30 kg/m2

You may not qualify if:

• psychiatric (DSM IV) disorders limiting the ability to comply with study
• use of medications influencing upper GI motility
• evidence of current drug or alcohol abuse
• history of gastrointestinal disease or surgery except appendicectomy or hernia repair

Sponsors & Collaborators

• University of Zurich: lead
• COOP: collaborator

Study Sites (1)

Unknown Facility

Zurich, Switzerland

Location

Related Publications (1)

• Heinrich H, Goetze O, Menne D, Iten PX, Fruehauf H, Vavricka SR, Schwizer W, Fried M, Fox M. Effect on gastric function and symptoms of drinking wine, black tea, or schnapps with a Swiss cheese fondue: randomised controlled crossover trial. BMJ. 2010 Dec 14;341:c6731. doi: 10.1136/bmj.c6731.

  PMID: 21156747 DERIVED

Study Officials

• 01 Studienregister MasterAdmins

  UniversitaetsSpital Zuerich

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: July 20, 2009
• First Posted: July 22, 2009
• Study Start: August 1, 2009
• Primary Completion: October 1, 2009
• Study Completion: October 1, 2009
• Last Updated: June 28, 2010

Record last verified: 2010-06

Locations

CH (1)