Study Stopped
Non availability of funding
Evaluation of New Markers to Assess Kidney Function
Validity and Reliability of a Novel GFR Marker
Non availability of funding
Validity and Reliability of a Novel GFR Marker
Sponsor study identifier
Secondary identifiers
observational
0
0 countries
N/A
Study Start
September 2009
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
September 2010
Actual (reported)Study Completion
September 2011
Actual (reported)Glomerular filtration rate (GFR) is widely accepted as the best index of kidney function in health and disease, and accurate values are required for optimal clinical decision making and in large-scale epidemiologic studies and clinical trials. Current recommended methods for measuring GFR are expensive, cumbersome to administer and assay and requires urine collection and administration of radioactive materials. The purpose of this study is to evaluate two non-radioactive markers (iohexol and gadolinium) compared to urinary clearance of inulin and iothalamate. The investigators hypothesize that plasma clearance of non-radioactive markers will be unbiased compared to a gold standard and more precise than currently used urinary clearance methods.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
September 2011
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 8, 2009
Actual (reported)July 14, 2009
Actual (reported)September 2009
Date type not reportedThis date has not been verified as actual or estimated.
September 2010
Actual (reported)September 2011
Actual (reported)Accuracy and precision of the different markers for measuring GFR
End points are not applicable. It's a cross-sectional design study
A cohort of 10 patients subjects with and without kidney disease exhibiting a broad range of age and kidney function
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Subjects with CKD and without CKD will be recruited to participate in the study. Subjects with CKD will be recruited primarily from the Kidney and Blood Pressure Center. Subjects without CKD will be recruited from advertisements as well as the volunteer database at the Jean Mayer Human Nutrition Research Center on Aging (HRNCA), which is located next to Tufts Medical Center.
Blood and urine will be retained for future testing
Lesley A Stevens, MD, MS
Tufts Medical Center
0 participants (actual enrollment reported by the registry).
First Submitted
July 8, 2009
First Posted
July 14, 2009
Study Start
September 2009
Date type not reportedThis date has not been verified as actual or estimated.
Quality Assessment Creatinines in Plasma and Urine
Contact the study team to confirm eligibility.
Primary Completion
September 2010
Actual (reported)Study Completion
September 2011
Actual (reported)Last Updated
July 13, 2016
Record last verified: 2016-07
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Source: ClinicalTrials.gov.
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