Human Papilloma Virus (HPV) Vaccination Among Rural African American Primary Caregivers and Daughters

NCT00937287 | Completed

• 1 other identifier: MISP 36701
• Study Type: observational
• Target: 410
• Locations: 1 country
• Sites: 1

Brief Summary

African American women living in the rural South are twice as likely as Caucasian women to develop cervical cancer and die of invasive cervical cancer at a higher rate than any other racial/ethnic group in the US (1). Reasons for low HPV vaccination rates among rural African Americans are not well understood. HPV vaccination compliance is likely influenced by barriers to health care access, misinformation regarding vaccinations, religious beliefs related to sexual health and behaviors, and mistrust of the medical community (2, 3). Because the vaccination of minors requires primary caregiver consent, vaccination commitment and compliance is strongly influenced by family beliefs and communication regarding health and sexuality. To date, little research has examined the cultural, familial, and intrapersonal influences on HPV vaccination compliance among rural African American women. This study will address these gaps in the literature and provide data needed to develop effective interventions and health promotion materials to encourage HPV vaccination among rural African American women. From a pool of approximately 800 families who are participating in ongoing longitudinal research through the Center for Family Research at the University of Georgia, the investigators will recruit 200 rural female African American youth aged 13-17 who have not received the HPV vaccine and their primary caregivers (n=200) into an observational, prospective study on vaccination commitment and compliance. The investigators hypotheses are as follows:

1. 1.Sociocultural factors that rural African Americans experience, including discrimination, previous health care experience, religious beliefs, and community norms regarding HPV vaccination and adolescent sexual behavior, will forecast primary caregivers' HPV vaccination commitment and compliance for their daughters. The investigators also predict that primary caregivers' HPV-related knowledge and attitudes will mediate this association.
2. 2.Sociocultural factors will influence sexual health-related family communication and interaction, primary caregivers' and youths' HPV-related attitudes, and HPV vaccination commitment and compliance.
3. 3.Primary caregivers' attitudes, youths' attitudes, and family health communication will contribute to youths' and caregivers' vaccination commitment and compliance.
4. 4.Youths' sexual behavior will influence their attitudes, family health communication, and vaccination commitment and compliance.

Conditions

Human Papillomavirus

Keywords

HPV; African American; Rural

Outcome Measures

Primary Outcomes (1)

• HPV vaccination compliance

  1 year

Study Arms (1)

youth and caregivers

Other: There is no intervention in this study.

Interventions

There is no intervention in this study. OTHER

No intervention is provided in this study as it is exploratory.

youth and caregivers

Eligibility Criteria

• Age: 13 Years - 17 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

The sample will include rural, female African American youth aged 13-17 (n=200) and their primary caregivers (n=200) who reside in the same household.

You may qualify if:

• Rural African American girls aged 13-17
• Female parent or primary caregiver of participating daughter

You may not qualify if:

• Girls can not be younger than age 13, or older than 17
• The target's female parent or primary caregiver must also live in the same household and agree to participate

Sponsors & Collaborators

• University of Georgia: lead

Study Sites (1)

The Center for Family Research

Athens, Georgia, 30602, United States

Location

Related Publications (3)

• Saraiya M, Ahmed F, Krishnan S, Richards TB, Unger ER, Lawson HW. Cervical cancer incidence in a prevaccine era in the United States, 1998-2002. Obstet Gynecol. 2007 Feb;109(2 Pt 1):360-70. doi: 10.1097/01.AOG.0000254165.92653.e8.

  PMID: 17267837 BACKGROUND

• Brewer NT, Fazekas KI. Predictors of HPV vaccine acceptability: a theory-informed, systematic review. Prev Med. 2007 Aug-Sep;45(2-3):107-14. doi: 10.1016/j.ypmed.2007.05.013. Epub 2007 Jun 2.

  PMID: 17628649 BACKGROUND

• Cates JR, Brewer NT, Fazekas KI, Mitchell CE, Smith JS. Racial differences in HPV knowledge, HPV vaccine acceptability, and related beliefs among rural, southern women. J Rural Health. 2009 Winter;25(1):93-7. doi: 10.1111/j.1748-0361.2009.00204.x.

  PMID: 19166567 BACKGROUND

Study Officials

• Stephanie R. Burwell, PhD

  University of Georgia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 9, 2009
• First Posted: July 10, 2009
• Study Start: July 1, 2009
• Primary Completion: April 1, 2011
• Study Completion: July 1, 2012
• Last Updated: August 14, 2013

Record last verified: 2013-08

Locations

US (1)