Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer
A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy With or Without Short-Term Androgen Deprivation Therapy for Patients With Intermediate-Risk Prostate Cancer
3 other identifiers
interventional
1,538
2 countries
518
Brief Summary
RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells and shrink tumors. Androgens can cause the growth of prostate cancer cells. Androgen-deprivation therapy may lessen the amount of androgens made by the body. It is not yet known whether radiation therapy is more effective with or without androgen-deprivation therapy in treating patients with prostate cancer. PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works compared with radiation therapy given together with androgen-deprivation therapy in treating patients with prostate cancer.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_3 prostate-cancer
Started Sep 2009
Longer than P75 for phase_3 prostate-cancer
518 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 8, 2009
CompletedFirst Posted
Study publicly available on registry
July 10, 2009
CompletedStudy Start
First participant enrolled
September 1, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 3, 2020
CompletedResults Posted
Study results publicly available
October 6, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
September 4, 2025
CompletedMarch 6, 2026
September 1, 2025
11.1 years
July 8, 2009
August 1, 2022
February 11, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Percentage of Participants Alive (Overall Survival)
Overall survival time is defined as time from randomization to the date of death from any cause or last known follow-up (censored). Overall survival rates are estimated by the Kaplan-Meier method. The protocol specifies that the distributions of failure times be compared between the arms, which is reported in the statistical analysis results. Five-year rates are provided here. Analysis was planned to occur after 218 deaths were reported.
From randomization to last follow-up. Follow-up schedule: end of RT (2nd arm only), then every 3 months for a year, every 4 months for 4 years, then yearly. Maximum follow-up at time of analysis was 10.3 years. Five-year rates reported here.
Secondary Outcomes (18)
Percentage of Participants With Biochemical Failure
From randomization to last follow-up. Follow-up schedule: end of RT (2nd arm only), then every 3 months for a year, every 4 months for 4 years, then yearly. Maximum follow-up at time of analysis was 10.3 years. Five-year rates reported here.
Percentage of Participants With Local Recurrence
From randomization to last follow-up. Follow-up schedule: end of RT (2nd arm only), then every 3 months for a year, every 4 months for 4 years, then yearly. Maximum follow-up at time of analysis was 10.3 years. Five-year rates reported here.
Percentage of Participants With Regional Recurrence
From randomization to last follow-up. Maximum follow-up at time of analysis was 10.3 years.
Percentage of Participants With Distant Metastasis
From randomization to last follow-up. Follow-up schedule: end of RT (2nd arm only), then every 3 months for a year, every 4 months for 4 years, then yearly. Maximum follow-up at time of analysis was 10.3 years. Five-year rates reported here.
Percentage of Participants Dead Due to Prostate Cancer (Prostate Cancer-specific Mortality)
From randomization to last follow-up. Follow-up schedule: end of RT (2nd arm only), then every 3 months for a year, every 4 months for 4 years, then yearly. Maximum follow-up at time of analysis was 10.3 years. Five-year rates reported here.
- +13 more secondary outcomes
Other Outcomes (2)
Percentage of Participants Alive (Overall Survival) by Ethnicity
From randomization to last follow-up. Follow-up schedule: end of RT (2nd arm only), then every 3 months for a year, every 4 months for 4 years, then yearly. Maximum follow-up at time of analysis was 10.3 years. Five-year rates reported here.
Percentage of Participants Alive (Overall Survival) by Race
From randomization to last follow-up. Follow-up schedule: end of RT (2nd arm only), then every 3 months for a year, every 4 months for 4 years, then yearly. Maximum follow-up at time of analysis was 10.3 years. Five-year rates reported here.
Study Arms (2)
Dose-Escalated Radiation Therapy Alone
ACTIVE COMPARATORRadiation therapy consists of 79.2 Gy EBRT only or 45 Gy EBRT followed by low- or high-dose rate brachytherapy. EBRT is delivered in 1.8 Gy daily fractions.
Dose-Escalated Radiation Therapy and Short-Term Androgen-Deprivation
EXPERIMENTALRadiation therapy consists of 79.2 Gy EBRT only or 45 Gy EBRT followed by low- or high-dose rate brachytherapy. EBRT is delivered in 1.8 Gy daily fractions. Six months of androgen-deprivation therapy starts 8 weeks prior to start of radiation therapy and consists of luteinizing-hormone releasing-hormone (LHRH) agonist (antagonist) therapy (leuprolide, goserelin, buserelin. triptorelin, or degarelix) and anti-androgen therapy (bicalutamide or flutamide).
Interventions
External beam radiotherapy (EBRT) as 3D Conformal Radiotherapy (3DCRT) or intensity-modulated radiation therapy (IMRT). Brachytherapy is optional, at the discretion of the treating physician. Patients treated entirely via EBRT receive 79.2 Gy delivered in 1.8 Gy fractions. Patients who receive brachytherapy as a component of their RT receive 45 Gy EBRT in 1.8 Gy fractions. Low-dose brachytherapy boost occurs following the EBRT portion of treatment no more than 4 weeks following its completion.High-dose rate brachytherapy boost is delivered in 2 fractions separated by a minimum time span of 6 hours and the implant(s) may be performed during the EBRT portion of the treatment or within 1 week prior to its initiation or following its completion.
Administered orally at a dose of 250 mg (two 125-mg capsules) three times a day for a total daily dose of 750 mg, beginning within (before, same day as, or after) 10 days of with the date of the first LHRH agonist (antagonist) therapy administration and continuing for a total duration of 6 months.
LHRH agonist (antagonist) therapy consists of leuprolide, goserelin, buserelin, triptorelin, or degarelix. The manufacturer's instructions should be followed. The first administration occurs with the start of anti-androgen treatment 8 weeks prior to the start of RT. The total duration of LHRH agonist (antagonist) therapy is 6 months.
Administered orally at a dose of one 50 mg tablet per day, beginning within (before, same day as, or after) 10 days of the date of the first LHRH agonist (antagonist) therapy administration and continuing for a total duration of 6 months.
Eligibility Criteria
You may qualify if:
- Pathologically (histologically) proven diagnosis of prostatic adenocarcinoma, at intermediate risk for recurrence, within 180 days prior to registration as determined by having one or more of the following intermediate-risk features: Gleason score 7; prostate-specific antigen (PSA) \>10 but ≤20; clinical stage T2b-T2c.
- Patients previously diagnosed with low risk (Gleason score ≤ 6, clinical stage \< T2a, and PSA \< 10) prostate cancer undergoing active surveillance who are re-biopsied and found to have intermediate risk disease according to the protocol criteria are eligible for enrollment within 180 days of the repeat biopsy procedure.
- Clinically negative lymph nodes as established by imaging (pelvic +/- abdominal CT or MRI), nodal sampling, or dissection within 60 days prior to registration, except as noted immediately below:
- Patients with a single intermediate risk factor only do not require abdominopelvic imaging, but these studies may be obtained at the discretion of the treating physician. Patients with 2 or 3 risk factors are required to undergo pelvic +/- abdominal CT or MRI.
- Patients with lymph nodes equivocal or questionable by imaging are eligible without biopsy if the nodes are ≤1.5 cm; any node larger than this on imaging will require negative biopsy for eligibility.
- No evidence of bone metastases (M0) on bone scan within 60 days prior to registration.
- Bone scan is not required for patients enrolled with a single intermediate risk factor only, but this scan may be obtained at the discretion of the treating physician. Patients with 2 or 3 risk factors will require a negative bone scan for eligibility.
- Equivocal bone scan findings are allowed if plain film x-rays are negative for metastasis.
- History/physical examination (to include, at a minimum, digital rectal examination of the prostate and examination of the skeletal system and abdomen, and formal comorbidity assessment via the ACE-27 instrument) within 60 days prior to registration.
- Zubrod Performance Status 0-1
- Age ≥ 18
- Baseline serum PSA value performed with an FDA-approved assay (e.g., Abbott, Hybritech) within 60 days prior to registration
- Study entry PSA must not be obtained during the following time frames: (1) 10-day period following prostate biopsy; (2) following initiation of ADT; (3) within 30 days after discontinuation of finasteride; or (4) within 90 days after discontinuation of dutasteride.
- For patients undergoing brachytherapy only: complete blood count (CBC)/differential obtained within 60 days prior to registration, with adequate bone marrow function defined as follows:
- Absolute neutrophil count (ANC) ≥ 1,800 cells/mm3
- +3 more criteria
You may not qualify if:
- Patients with Gleason Score ≥ 8; PSA \> 20; OR Clinical Stage ≥ T3 are ineligible for this trial.
- Should findings of extracapsular extension or seminal vesicle invasion be noted on prostate MRI, this study, if used, will not render patients ineligible for accrual to this protocol. Primary tumor staging for eligibility purposes is to be based on palpable or core biopsy evidence only with respect to extracapsular extension or seminal vesicle involvement.
- Patients with all three intermediate risk factors who also have ≥ 50% of the number of their biopsy cores positive for cancer are ineligible for this trial.
- Prior invasive malignancy (except non-melanomatous skin cancer) or hematological (e.g., leukemia, lymphoma, myeloma) malignancy unless disease free for a minimum of 5 years (prior diagnoses of carcinoma in situ are permitted)
- Prior radical surgery (prostatectomy), high-intensity focused ultrasound (HIFU) or cryosurgery for prostate cancer
- Prior hormonal therapy, such as LHRH agonists (e.g., goserelin, leuprolide), antiandrogens (e.g., flutamide, bicalutamide), estrogens (e.g., DES), or bilateral orchiectomy
- Use of finasteride within 30 days prior to registration
- Use of dutasteride within 90 days prior to registration
- Prior or concurrent cytotoxic chemotherapy for prostate cancer; prior chemotherapy for a different cancer is permitted.
- Prior RT, including brachytherapy, to the region of the study cancer that would result in overlap of RT fields
- Any patient undergoing brachytherapy must have transrectal ultrasound confirmation of prostate volume \<60 cc, American Urological Association Symptom Index (AUA-SI) score ≤15 within 60 days of registration, and no history of prior transurethral resection of the prostate (TURP); prior TURP is permitted for patients who receive EBRT only)
- Severe, active co-morbidity, defined as follows:
- Unstable angina and/or congestive heart failure requiring hospitalization within the last 6 months
- Transmural myocardial infarction within the last 6 months
- Acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration
- +3 more criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Radiation Therapy Oncology Grouplead
- National Cancer Institute (NCI)collaborator
- NRG Oncologycollaborator
Study Sites (518)
University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, 35233, United States
Fairbanks Memorial Hospital
Fairbanks, Alaska, 99701, United States
Arizona Center for Cancer Care-Peoria
Peoria, Arizona, 85381, United States
Saint Joseph's Hospital and Medical Center
Phoenix, Arizona, 85013, United States
21st Century Oncology-Scottsdale
Scottsdale, Arizona, 85251, United States
Mayo Clinic in Arizona
Scottsdale, Arizona, 85259, United States
Arizona Oncology Services Foundation
Scottsdale, Arizona, 85260, United States
Arizona Oncology Associates-West Orange Grove
Tucson, Arizona, 85704, United States
Mercy Cancer Center-Hot Springs
Hot Springs, Arkansas, 71913, United States
Sutter Cancer Centers Radiation Oncology Services-Auburn
Auburn, California, 95603, United States
Alta Bates Summit Medical Center-Herrick Campus
Berkeley, California, 94704, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California, 91505, United States
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Cameron Park, California, 95682, United States
Mercy San Juan Medical Center
Carmichael, California, 95608, United States
Enloe Medical Center
Chico, California, 95926, United States
21st Century Oncology - El Segundo
El Segundo, California, 90245, United States
Fresno Cancer Center
Fresno, California, 93720, United States
Saint Agnes Medical Center
Fresno, California, 93720, United States
Marin General Hospital
Greenbrae, California, 94904, United States
Veterans Administration Long Beach Medical Center
Long Beach, California, 90822, United States
Los Angeles County-USC Medical Center
Los Angeles, California, 90033, United States
USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
Memorial Medical Center
Modesto, California, 95355, United States
Kaiser Permanente Oakland-Broadway
Oakland, California, 94611, United States
Kaiser Permanente-Oakland
Oakland, California, 94611, United States
Desert Regional Medical Center
Palm Springs, California, 92262, United States
Stanford Cancer Institute
Palo Alto, California, 94304, United States
Feather River Cancer Center
Paradise, California, 95969, United States
Pomona Valley Hospital Medical Center
Pomona, California, 91767, United States
Kaiser Permanente-Rancho Cordova Cancer Center
Rancho Cardova, California, 95670, United States
Kaiser Permanente-Redwood City
Redwood City, California, 94063, United States
Kaiser Permanente-Richmond
Richmond, California, 94801, United States
Rohnert Park Cancer Center
Rohnert Park, California, 94928, United States
Kaiser Permanente-Roseville
Roseville, California, 95661, United States
Sutter Cancer Centers Radiation Oncology Services-Roseville
Roseville, California, 95661, United States
The Permanente Medical Group-Roseville Radiation Oncology
Roseville, California, 95678, United States
Sutter General Hospital
Sacramento, California, 95816, United States
University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
Mercy General Hospital Radiation Oncology Center
Sacramento, California, 95819, United States
Kaiser Permanente-South Sacramento
Sacramento, California, 95823, United States
South Sacramento Cancer Center
Sacramento, California, 95823, United States
Kaiser Permanente - Sacramento
Sacramento, California, 95825, United States
University of California San Diego
San Diego, California, 92103, United States
Kaiser Permanente-San Francisco
San Francisco, California, 94115, United States
UCSF Medical Center-Mount Zion
San Francisco, California, 94115, United States
California Pacific Medical Center-Pacific Campus
San Francisco, California, 94118, United States
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, 95119, United States
Kaiser Permanente San Leandro
San Leandro, California, 94577, United States
Kaiser Permanente-San Rafael
San Rafael, California, 94903, United States
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, 95051, United States
Kaiser Permanente-Santa Rosa
Santa Rosa, California, 95403, United States
Kaiser Permanente Cancer Treatment Center
South San Francisco, California, 94080, United States
Kaiser Permanente-South San Francisco
South San Francisco, California, 94080, United States
Kaiser Permanente-Stockton
Stockton, California, 95210, United States
David Grant United States Air Force Medical Center
Travis AFB, California, 94535-1800, United States
Tahoe Forest Cancer Center
Truckee, California, 96161, United States
Sutter Cancer Centers Radiation Oncology Services-Vacaville
Vacaville, California, 95687, United States
Sutter Solano Medical Center/Cancer Center
Vallejo, California, 94589, United States
Kaiser Permanente-Walnut Creek
Walnut Creek, California, 94596, United States
Rocky Mountain Cancer Centers-Aurora
Aurora, Colorado, 80012, United States
University of Colorado Cancer Center - Anschutz Cancer Pavilion
Aurora, Colorado, 80045, United States
The Urology Center of Colorado
Denver, Colorado, 80211, United States
The Shaw Regional Cancer Center
Edwards, Colorado, 81632, United States
Poudre Valley Hospital
Fort Collins, Colorado, 80524, United States
Saint Mary's Hospital and Regional Medical Center
Grand Junction, Colorado, 81502, United States
Rocky Mountain Cancer Centers-Littleton
Littleton, Colorado, 80120, United States
Hartford Hospital
Hartford, Connecticut, 06102, United States
Saint Francis Hospital and Medical Center
Hartford, Connecticut, 06105, United States
Yale-New Haven Hospital Saint Raphael Campus
Hew Haven, Connecticut, 06511, United States
Midstate Medical Center
Meriden, Connecticut, 06451, United States
The Hospital of Central Connecticut
New Britain, Connecticut, 06050, United States
Helen F Graham Cancer Center
Newark, Delaware, 19713, United States
Christiana Care Health System-Christiana Hospital
Newark, Delaware, 19718, United States
University of Miami Sylvester Comprehensive Cancer Center at Deerfield Beach
Deerfield Beach, Florida, 33442, United States
Broward Health Medical Center
Fort Lauderdale, Florida, 33316, United States
Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980, United States
Florida Hospital Kissimmee
Kissimmee, Florida, 34744, United States
Lakeland Regional Cancer Center
Lakeland, Florida, 33805, United States
The Watson Clinic
Lakeland, Florida, 33805, United States
Jackson Memorial Hospital-Holtz Children's Hospital
Miami, Florida, 33136, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, 33136, United States
South Miami Hospital
Miami, Florida, 33143, United States
Florida Hospital Orlando
Orlando, Florida, 32803, United States
Bay Medical Center
Panama City, Florida, 32401, United States
James A. Haley Veterans Affairs Hospital
Tampa, Florida, 33612, United States
Grady Health System
Atlanta, Georgia, 30303, United States
Piedmont Hospital
Atlanta, Georgia, 30309, United States
Emory University/Winship Cancer Institute
Atlanta, Georgia, 30322, United States
Northside Hospital
Atlanta, Georgia, 30342, United States
John B Amos Cancer Center
Columbus, Georgia, 31904, United States
Northside Hospital-Forsyth
Cumming, Georgia, 30041, United States
Atlanta VA Medical Center
Decatur, Georgia, 30033, United States
Piedmont Fayette Hospital
Fayetteville, Georgia, 30214, United States
Northeast Georgia Medical Center
Gainesville, Georgia, 30501, United States
Memorial University Medical Center
Savannah, Georgia, 31404, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Savannah, Georgia, 31405, United States
Queen's Medical Center
Honolulu, Hawaii, 96813, United States
University of Hawaii Cancer Center
Honolulu, Hawaii, 96813, United States
The Cancer Center of Hawaii-Liliha
Honolulu, Hawaii, 96817, United States
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho, 83706, United States
Idaho Urologic Institute-Meridian
Meridian, Idaho, 83642, United States
Kootenai Cancer Center
Post Falls, Idaho, 83854, United States
Saint Anthony's Health
Alton, Illinois, 62002, United States
Memorial Hospital of Carbondale
Carbondale, Illinois, 62902, United States
Northwestern University
Chicago, Illinois, 60611, United States
John H Stroger Jr Hospital of Cook County
Chicago, Illinois, 60612-3785, United States
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637, United States
Advocate Illinois Masonic Medical Center
Chicago, Illinois, 60657, United States
Decatur Memorial Hospital
Decatur, Illinois, 62526, United States
Crossroads Cancer Center
Effingham, Illinois, 62401, United States
Hines Veterans Administration Hospital
Hines, Illinois, 60141, United States
Loyola University Medical Center
Maywood, Illinois, 60153, United States
Pekin Cancer Treatment Center
Pekin, Illinois, 61554, United States
OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC
Peoria, Illinois, 61615-7827, United States
OSF Saint Francis Medical Center
Peoria, Illinois, 61637, United States
SwedishAmerican Regional Cancer Center/ACT
Rockford, Illinois, 61114, United States
Saint John's Hospital
Springfield, Illinois, 62702, United States
Memorial Medical Center
Springfield, Illinois, 62781-0001, United States
Memorial and Saint Elizabeth's Health Care Services LLP
Swansea, Illinois, 62226, United States
Saint Vincent Anderson Regional Hospital/Cancer Center
Anderson, Indiana, 46016, United States
IU Health West Hospital
Avon, Indiana, 46123, United States
IU Health Bloomington
Bloomington, Indiana, 47403, United States
Radiation Oncology Associates PC
Fort Wayne, Indiana, 46804, United States
Parkview Hospital Randallia
Fort Wayne, Indiana, 46805, United States
IU Health Goshen Center for Cancer Care
Goshen, Indiana, 46526, United States
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, 46202, United States
IU Health Methodist Hospital
Indianapolis, Indiana, 46202, United States
Richard L. Roudebush Veterans Affairs Medical Center
Indianapolis, Indiana, 46202, United States
IU Health Central Indiana Cancer Centers-East
Indianapolis, Indiana, 46219, United States
McFarland Clinic PC-William R Bliss Cancer Center
Ames, Iowa, 50010, United States
Medical Oncology and Hematology Associates-West Des Moines
Clive, Iowa, 50325, United States
Iowa Methodist Medical Center
Des Moines, Iowa, 50309, United States
Iowa Oncology Research Association CCOP
Des Moines, Iowa, 50309, United States
Medical Oncology and Hematology Associates-Des Moines
Des Moines, Iowa, 50309, United States
Medical Oncology and Hematology Associates-Laurel
Des Moines, Iowa, 50314, United States
Mercy Medical Center - Des Moines
Des Moines, Iowa, 50314, United States
Iowa Lutheran Hospital
Des Moines, Iowa, 50316, United States
Finley Hospital
Dubuque, Iowa, 52001, United States
Cancer Center of Kansas - Dodge City
Dodge City, Kansas, 67801, United States
Cancer Center of Kansas - El Dorado
El Dorado, Kansas, 67042, United States
Lawrence Memorial Hospital
Lawrence, Kansas, 66044, United States
Kansas City Cancer Centers-Southwest
Overland Park, Kansas, 66210, United States
Cancer Center of Kansas - Wellington
Wellington, Kansas, 67152, United States
Associates In Womens Health
Wichita, Kansas, 67208, United States
Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita, Kansas, 67208, United States
Cancer Center of Kansas - Main Office
Wichita, Kansas, 67214, United States
Via Christi Regional Medical Center
Wichita, Kansas, 67214, United States
Wesley Medical Center
Wichita, Kansas, 67214, United States
Wichita CCOP
Wichita, Kansas, 67214, United States
Cancer Center of Kansas - Winfield
Winfield, Kansas, 67156, United States
Baptist Health Lexington
Lexington, Kentucky, 40503, United States
University of Kentucky/Markey Cancer Center
Lexington, Kentucky, 40536, United States
The James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky, 40202, United States
Owensboro Health Mitchell Memorial Cancer Center
Owensboro, Kentucky, 42303, United States
Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana, 70809, United States
Tulane University Health Sciences Center
New Orleans, Louisiana, 70112, United States
Ochsner Medical Center Jefferson
New Orleans, Louisiana, 70121, United States
Central Maine Medical Center
Lewiston, Maine, 04240, United States
Maine Medical Center- Scarborough Campus
Scarborough, Maine, 04074, United States
Anne Arundel Medical Center
Annapolis, Maryland, 21401, United States
University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland, 21201, United States
Greater Baltimore Medical Center
Baltimore, Maryland, 21204, United States
Saint Agnes Hospital
Baltimore, Maryland, 21229, United States
Upper Chesapeake Medical Center
Bel Air, Maryland, 21015, United States
Walter Reed National Military Medical Center
Bethesda, Maryland, 20889-5600, United States
Central Maryland Radiation Oncology in Howard County
Columbia, Maryland, 21044, United States
Tate Cancer Center
Glen Burnie, Maryland, 21061, United States
Holy Cross Hospital
Silver Spring, Maryland, 20910, United States
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114, United States
Boston Medical Center
Boston, Massachusetts, 02118, United States
Mass General/North Shore Cancer Center
Danvers, Massachusetts, 01923, United States
Saint Anne's Hospital
Fall River, Massachusetts, 02721, United States
Cape Cod Hospital
Hyannis, Massachusetts, 02601, United States
Lowell General Hospital
Lowell, Massachusetts, 01854, United States
Berkshire Hematology Oncology PC
Pittsfield, Massachusetts, 01201, United States
Beth Israel Deaconess Hospital-Plymouth
Plymouth, Massachusetts, 02360, United States
D'Amour Center for Cancer Care
Springfield, Massachusetts, 01107, United States
Baystate Medical Center
Springfield, Massachusetts, 01199, United States
Saint Vincent Hospital/Reliant Medical Group
Worcester, Massachusetts, 01608, United States
Bixby Medical Center
Adrian, Michigan, 49221, United States
Veteran's Administration Medical Center - Ann Arbor
Ann Arbor, Michigan, 48105, United States
Saint Joseph Mercy Hospital
Ann Arbor, Michigan, 48106-0995, United States
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, 48109, United States
Bronson Battle Creek
Battle Creek, Michigan, 49017, United States
McLaren-Bay Region
Bay City, Michigan, 48708, United States
Henry Ford Macomb Hospital
Clinton Township, Michigan, 48038, United States
Huron Valley-Sinai Hospital
Commerce, Michigan, 48382, United States
Henry Ford Hospital
Detroit, Michigan, 48202, United States
Saint John Hospital and Medical Center
Detroit, Michigan, 48236, United States
Green Bay Oncology - Escanaba
Escanaba, Michigan, 49431, United States
Botsford General Hospital
Farmington, Michigan, 48334, United States
21st Century Oncology-Farmington Hills
Farmington Hills, Michigan, 48334, United States
Genesys Hurley Cancer Institute
Flint, Michigan, 48503, United States
Genesys Regional Medical Center-West Flint Campus
Flint, Michigan, 48532, United States
McLaren-Flint
Flint, Michigan, 48532, United States
Mercy Health Saint Mary's
Grand Rapids, Michigan, 49503, United States
Spectrum Health at Butterworth Campus
Grand Rapids, Michigan, 49503, United States
Green Bay Oncology - Iron Mountain
Iron Mountain, Michigan, 49801, United States
Borgess Medical Center
Kalamazoo, Michigan, 49001, United States
Bronson Methodist Hospital
Kalamazoo, Michigan, 49007, United States
West Michigan Cancer Center
Kalamazoo, Michigan, 49007, United States
Sparrow Hospital
Lansing, Michigan, 48912, United States
Great Lakes Cancer Institute-Lapeer Campus
Lapeer, Michigan, 48446, United States
McLaren-Macomb
Mount Clemens, Michigan, 48043, United States
McLaren-Central Michigan
Mount Pleasant, Michigan, 48858, United States
Mercy Health Mercy Campus
Muskegon, Michigan, 49444, United States
McLaren Cancer Institute-Owosso
Owosso, Michigan, 48867, United States
Northern Michigan Regional Hospital
Petoskey, Michigan, 49770, United States
Saint Joseph Mercy Oakland
Pontiac, Michigan, 48341, United States
Saint Joseph Mercy Port Huron
Port Huron, Michigan, 48060, United States
Crittenton Hospital
Rochester, Michigan, 48307, United States
William Beaumont Hospital-Royal Oak
Royal Oak, Michigan, 48073, United States
Saint Mary's of Michigan
Saginaw, Michigan, 48601, United States
Downriver Center for Oncology
Trenton, Michigan, 48183, United States
21st Century Oncology-Troy
Troy, Michigan, 48098, United States
William Beaumont Hospital - Troy
Troy, Michigan, 48098, United States
Saint John Macomb-Oakland Hospital
Warren, Michigan, 48093, United States
Henry Ford West Bloomfield Hospital
West Bloomfield, Michigan, 48322, United States
Mayo Clinic Health System in Albert Lea
Albert Lea, Minnesota, 56007, United States
Sanford Clinic North-Bemidgi
Bemidji, Minnesota, 56601, United States
Miller-Dwan Hospital
Duluth, Minnesota, 55805, United States
Saint Luke's Hospital of Duluth
Duluth, Minnesota, 55805, United States
Fairview-Southdale Hospital
Edina, Minnesota, 55435, United States
Mayo Clinic Health Systems-Mankato
Mankato, Minnesota, 56001, United States
Mayo Clinic
Rochester, Minnesota, 55905, United States
Regions Hospital
Saint Paul, Minnesota, 55101, United States
Saint Francis Medical Center
Cape Girardeau, Missouri, 63703, United States
Siteman Cancer Center - Saint Peters
City of Saint Peters, Missouri, 63376, United States
Mercy Hospital-Joplin
Joplin, Missouri, 64804, United States
Kansas City Cancer Center - South
Kansas City, Missouri, 64131, United States
Kansas City Cancer Centers - North
Kansas City, Missouri, 64154, United States
Kansas City Cancer Center-Lee's Summit
Lee's Summit, Missouri, 64064, United States
Phelps County Regional Medical Center
Rolla, Missouri, 65401, United States
Cancer Research for the Ozarks NCORP
Springfield, Missouri, 65804, United States
Mercy Hospital Springfield
Springfield, Missouri, 65804, United States
CoxHealth South Hospital
Springfield, Missouri, 65807, United States
Washington University School of Medicine
St Louis, Missouri, 63110, United States
Siteman Cancer Center-South County
St Louis, Missouri, 63129, United States
Missouri Baptist Medical Center
St Louis, Missouri, 63131, United States
Barnes-Jewish West County Hospital
St Louis, Missouri, 63141, United States
Mercy Hospital Saint Louis
St Louis, Missouri, 63141, United States
Saint Louis-Cape Girardeau CCOP
St Louis, Missouri, 63141, United States
Montana Cancer Consortium CCOP
Billings, Montana, 59101, United States
Northern Rockies Radiation Oncology Center
Billings, Montana, 59101, United States
Billings Clinic Cancer Center
Billings, Montana, 59107, United States
Berdeaux, Donald MD (UIA Investigator)
Great Falls, Montana, 59405, United States
Great Falls Clinic
Great Falls, Montana, 59405, United States
Saint Elizabeth Regional Medical Center
Lincoln, Nebraska, 68510, United States
Missouri Valley Cancer Consortium
Omaha, Nebraska, 68106, United States
Nebraska Methodist Hospital
Omaha, Nebraska, 68114, United States
Alegent Health Immanuel Medical Center
Omaha, Nebraska, 68122, United States
Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska, 68124, United States
Alegent Health Lakeside Hospital
Omaha, Nebraska, 68130, United States
Creighton University Medical Center
Omaha, Nebraska, 68131, United States
University of Nebraska Medical Center
Omaha, Nebraska, 68198, United States
Concord Hospital
Concord, New Hampshire, 03301, United States
Exeter Hospital
Exeter, New Hampshire, 03833, United States
Cheshire Medical Center-Dartmouth-Hitchcock Keene
Keene, New Hampshire, 03431, United States
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, 03756, United States
Elliot Hospital
Manchester, New Hampshire, 03103, United States
Ocean Medical Center
Brick, New Jersey, 08724, United States
Cooper Hospital University Medical Center
Camden, New Jersey, 08103, United States
Veterans Adminstration New Jersey Health Care System
East Orange, New Jersey, 07018-1095, United States
CentraState Medical Center
Freehold, New Jersey, 07728, United States
Princeton Radiation Oncology Center
Monroe, New Jersey, 08831, United States
Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington County
Mount Holly, New Jersey, 08060, United States
Jersey Shore Medical Center
Neptune City, New Jersey, 07753, United States
Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903, United States
UMDNJ - Robert Wood Johnson University Hospital
New Brunswick, New Jersey, 08903, United States
UMDNJ - New Jersey Medical School
Newark, New Jersey, 07103, United States
Newark Beth Israel Medical Center
Newark, New Jersey, 07112, United States
The Medical Center At Princeton
Princeton, New Jersey, 08540-3298, United States
Riverview Medical Center/Booker Cancer Center
Red Bank, New Jersey, 07701, United States
Sparta Cancer Treatment Center
Sparta, New Jersey, 07871, United States
Community Medical Center
Toms River, New Jersey, 08755, United States
MD Anderson Cancer Center at Cooper-Voorhees
Voorhees Township, New Jersey, 08043, United States
Virtua West Jersey Hospital Voorhees
Voorhees Township, New Jersey, 08043, United States
Prostate Cancer Center of New Jersey
West Orange, New Jersey, 07052, United States
Lovelace Medical Center-Downtown
Albuquerque, New Mexico, 87102, United States
University of New Mexico
Albuquerque, New Mexico, 87102, United States
University of New Mexico Cancer Center
Albuquerque, New Mexico, 87106, United States
Radiation Oncology Associates
Albuquerque, New Mexico, 87109, United States
Memorial Medical Center - Las Cruces
Las Cruces, New Mexico, 88011, United States
New York Oncology Hematology PC - Albany
Albany, New York, 12206, United States
Saint Peters Hospital-Albany
Albany, New York, 12208, United States
Southside Hospital
Bay Shore, New York, 11706, United States
Lourdes Hospital
Binghamton, New York, 13905, United States
State University of New York Downstate Medical Center
Brooklyn, New York, 11203, United States
Veteran Affairs New York Harbor Healthcare System-Brooklyn Campus
Brooklyn, New York, 11209, United States
Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
Sands Cancer Center
Canandiaqua, New York, 14424, United States
Mary Imogene Bassett Hospital
Cooperstown, New York, 13326, United States
Arnot Ogden Medical Center/Falck Cancer Center
Elmira, New York, 14905, United States
North Shore University Hospital
Manhasset, New York, 11030, United States
North Shore-LIJ Health System NCORP
Manhasset, New York, 11030, United States
Long Island Jewish Medical Center
New Hyde Park, New York, 11040, United States
North Shore-LIJ Health System/Center for Advanced Medicine
New Hyde Park, New York, 11040, United States
Columbia University Medical Center
New York, New York, 10032, United States
Hudson Valley Oncology Associates
Poughkeepsie, New York, 12601, United States
Highland Hospital
Rochester, New York, 14620, United States
University Radiation Oncology
Rochester, New York, 14626, United States
University of Rochester
Rochester, New York, 14642, United States
Randolph Hospital
Asheboro, North Carolina, 27203, United States
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
Duke University Medical Center
Durham, North Carolina, 27710, United States
Cone Health Cancer Center
Greensboro, North Carolina, 27403, United States
The Coleman Radiation Center-Carteret General Hospital
Morehead City, North Carolina, 28557, United States
CarolinaEast Health System-Medical Center
New Bern, North Carolina, 28560, United States
Duke Cancer Institute Macon Pond
Raleigh, North Carolina, 27607, United States
Rex Cancer Center
Raleigh, North Carolina, 27607, United States
South Atlantic Radiation Oncology
Supply, North Carolina, 28462, United States
Coastal Carolina Radiation Oncology
Wilmington, North Carolina, 28401, United States
New Hanover Regional Medical Center/Zimmer Cancer Center
Wilmington, North Carolina, 28401, United States
Southeast Cancer Consortium-Upstate NCORP
Winston-Salem, North Carolina, 27104, United States
Mid Dakota Clinic
Bismarck, North Dakota, 58501, United States
Saint Alexius Medical Center
Bismarck, North Dakota, 58501, United States
Sanford Bismarck Medical Center
Bismarck, North Dakota, 58501, United States
Sanford Clinic North-Fargo
Fargo, North Dakota, 58122, United States
Sanford Medical Center-Fargo
Fargo, North Dakota, 58122, United States
Trinity Cancer Care Center
Minot, North Dakota, 58701, United States
Summa Akron City Hospital/Cooper Cancer Center
Akron, Ohio, 44304, United States
Akron General Medical Center
Akron, Ohio, 44307, United States
Summa Barberton Hospital
Barberton, Ohio, 44203, United States
UHHS-Chagrin Highlands Medical Center
Beachwood, Ohio, 44122, United States
Geaugra Hospital
Chardon, Ohio, 44024, United States
Adena Regional Medical Center
Chillicothe, Ohio, 45601, United States
University of Cincinnati
Cincinnati, Ohio, 45267, United States
Case Western Reserve University
Cleveland, Ohio, 44106, United States
Cleveland Clinic Cancer Center/Fairview Hospital
Cleveland, Ohio, 44111, United States
Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
Riverside Methodist Hospital
Columbus, Ohio, 43214, United States
Columbus CCOP
Columbus, Ohio, 43215, United States
Grant Medical Center
Columbus, Ohio, 43215, United States
The Mark H Zangmeister Center
Columbus, Ohio, 43219, United States
Mount Carmel Health Center West
Columbus, Ohio, 43222, United States
Doctors Hospital
Columbus, Ohio, 43228, United States
Grady Memorial Hospital
Delaware, Ohio, 43015, United States
Mercy Cancer Center-Elyria
Elyria, Ohio, 44035, United States
Cleveland Clinic Cancer Center Independence
Independence, Ohio, 44131, United States
Marietta Memorial Hospital
Marietta, Ohio, 45750, United States
Toledo Clinic Cancer Centers-Maumee
Maumee, Ohio, 43537, United States
Hillcrest Hospital Cancer Center
Mayfield Heights, Ohio, 44124, United States
Summa Health Center at Lake Medina
Medina, Ohio, 44256, United States
Lake University Ireland Cancer Center
Mentor, Ohio, 44060, United States
Southwest General Health Center Ireland Cancer Center
Middleburg Heights, Ohio, 44130, United States
Licking Memorial Hospital
Newark, Ohio, 43055, United States
Saint Charles Hospital
Oregon, Ohio, 43616, United States
University Hospitals Parma Medical Center
Parma, Ohio, 44129, United States
Southern Ohio Medical Center
Portsmouth, Ohio, 45662, United States
Robinson Radiation Oncology
Ravenna, Ohio, 44266, United States
Cancer Care Center, Incorporated
Salem, Ohio, 44460, United States
Ireland Cancer Center at Firelands Regional Medical Center
Sandusky, Ohio, 44870, United States
North Coast Cancer Care
Sandusky, Ohio, 44870, United States
Flower Hospital
Sylvania, Ohio, 43560, United States
University of Toledo
Toledo, Ohio, 43614, United States
Mercy Saint Anne Hospital
Toledo, Ohio, 43623, United States
University Pointe
West Chester, Ohio, 45069, United States
Saint Ann's Hospital
Westerville, Ohio, 43081, United States
UHHS-Westlake Medical Center
Westlake, Ohio, 44145, United States
Cancer Treatment Center
Wooster, Ohio, 44691, United States
Cleveland Clinic Wooster Specialty Center
Wooster, Ohio, 44691, United States
Wright-Patterson Medical Center
Wright-Patterson AFB, Ohio, 45433-5529, United States
Genesis HealthCare System
Zanesville, Ohio, 43701, United States
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104, United States
Clackamas Radiation Oncology Center
Clackamas, Oregon, 97015, United States
Willamette Valley Cancer Center
Eugene, Oregon, 97401, United States
Three Rivers Community Hospital
Grants Pass, Oregon, 97527, United States
Legacy Mount Hood Medical Center
Gresham, Oregon, 97030, United States
Asante Health System
Medford, Oregon, 97504, United States
Providence Medford Medical Center
Medford, Oregon, 97504, United States
Rogue Valley Medical Center
Medford, Oregon, 97504, United States
Providence Milwaukie Hospital
Milwaukie, Oregon, 97222, United States
Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon, 97210, United States
Providence Portland Medical Center
Portland, Oregon, 97213, United States
Western Oncology Research Consortium
Portland, Oregon, 97213, United States
Providence Saint Vincent Medical Center
Portland, Oregon, 97225, United States
Legacy Meridian Park Hospital
Tualatin, Oregon, 97062, United States
Abington Memorial Hospital
Abington, Pennsylvania, 19001, United States
Saint Luke's University Hospital-Bethlehem Campus
Bethlehem, Pennsylvania, 18015, United States
Bryn Mawr Hospital
Bryn Mawr, Pennsylvania, 19010, United States
Geisinger Medical Center
Danville, Pennsylvania, 17822, United States
Mercy Fitzgerald Hospital
Darby, Pennsylvania, 19023-1291, United States
Delaware County Memorial Hospital
Drexel Hill, Pennsylvania, 19026, United States
Northeast Radiation Oncology Center
Dunmore, Pennsylvania, 18512, United States
The Regional Cancer Center
Erie, Pennsylvania, 16505, United States
Fox Chase Cancer Center Buckingham
Furlong, Pennsylvania, 18925, United States
Adams Cancer Center
Gettysburg, Pennsylvania, 17325, United States
Cherry Tree Cancer Center
Hanover, Pennsylvania, 17331, United States
Penn State Milton S Hershey Medical Center
Hershey, Pennsylvania, 17033-0850, United States
Academic Urology Prostate Center
King of Prussia, Pennsylvania, 19406, United States
Saint Mary Medical and Regional Cancer Center
Langhorne, Pennsylvania, 19047, United States
Upper Delaware Valley Cancer Center
Milford, Pennsylvania, 18337, United States
Paoli Memorial Hospital
Paoli, Pennsylvania, 19301, United States
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States
Fox Chase Cancer Center
Philadelphia, Pennsylvania, 19111, United States
Temple University Hospital
Philadelphia, Pennsylvania, 19140, United States
Albert Einstein Medical Center
Philadelphia, Pennsylvania, 19141, United States
VA Pittsburgh Healthcare System
Pittsburgh, Pennsylvania, 15240, United States
Reading Hospital
West Reading, Pennsylvania, 19611, United States
Lankenau Medical Center
Wynnewood, Pennsylvania, 19096, United States
Mainline Health CCOP
Wynnewood, Pennsylvania, 19096, United States
WellSpan Health-York Hospital
York, Pennsylvania, 17405, United States
AnMed Health Hospital
Anderson, South Carolina, 29621, United States
Medical University of South Carolina
Charleston, South Carolina, 29425, United States
Greenville Health System Cancer Institute-Faris
Greenville, South Carolina, 29605, United States
Greenville Health System Cancer Institute-Eastside
Greenville, South Carolina, 29615, United States
Self Regional Healthcare
Greenwood, South Carolina, 29646, United States
Greenville Health System Cancer Institute-Greer
Greer, South Carolina, 29650, United States
Gibbs Cancer Center-Pelham
Greer, South Carolina, 29651, United States
Carolina Regional Cancer Center
Myrtle Beach, South Carolina, 29577, United States
Greenville Health System Cancer Institute-Seneca
Seneca, South Carolina, 29672, United States
Spartanburg Medical Center
Spartanburg, South Carolina, 29303, United States
Greenville Health System Cancer Institute-Spartanburg
Spartanburg, South Carolina, 29307, United States
Rapid City Regional Hospital
Rapid City, South Dakota, 57701, United States
Wellmont Holston Valley Hospital and Medical Center
Kingsport, Tennessee, 37660, United States
Thompson Cancer Survival Center
Knoxville, Tennessee, 37916, United States
Blount Memorial Hospital
Maryville, Tennessee, 37804, United States
Texas Oncology-Arlington South
Arlington, Texas, 76014, United States
Texas Oncology-Austin Midtown
Austin, Texas, 78705, United States
Texas Oncology - Central Austin Cancer Center
Austin, Texas, 78731, United States
Texas Oncology - South Austin Cancer Center
Austin, Texas, 78745, United States
Texas Oncology Bedford
Bedford, Texas, 76022, United States
Texas Cancer Center - Medical City Dallas
Dallas, Texas, 75230, United States
Texas Oncology Methodist Charlton Cancer Center
Dallas, Texas, 75237, United States
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, 75390, United States
Texas Oncology-Denton South
Denton, Texas, 76210, United States
Brooke Army Medical Center
Fort Sam Houston, Texas, 78234, United States
The Klabzuba Cancer Center
Fort Worth, Texas, 76104, United States
University of Texas Medical Branch
Galveston, Texas, 77555-0565, United States
Memorial Hermann Memorial City Medical Center
Houston, Texas, 77024, United States
M D Anderson Cancer Center
Houston, Texas, 77030, United States
UTMB Cancer Center at Victory Lakes
League City, Texas, 77573, United States
Texas Oncology - Lewisville
Lewisville, Texas, 75067, United States
Texas Oncology-Longview Cancer Center
Longview, Texas, 75601, United States
West Texas Cancer Center
Odessa, Texas, 79761, United States
Texas Oncology-Seton Williamson
Round Rock, Texas, 78665, United States
Texas Oncology - Round Rock Cancer Center
Round Rock, Texas, 78681, United States
Texas Cancer Center-Sherman
Sherman, Texas, 75090, United States
Texas Oncology Cancer Center Sugar Land
Sugar Land, Texas, 77479, United States
Texas Oncology-Wichita Falls Texoma Cancer Center
Wichita Falls, Texas, 76310, United States
Sandra L Maxwell Cancer Center
Cedar City, Utah, 84720, United States
Intermountain Medical Center
Murray, Utah, 84157, United States
McKay-Dee Hospital Center
Ogden, Utah, 84403, United States
Utah Valley Regional Medical Center
Provo, Utah, 84604, United States
Utah Cancer Specialists-Salt Lake City
Salt Lake City, Utah, 84106, United States
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112, United States
LDS Hospital
Salt Lake City, Utah, 84143, United States
Dixie Medical Center Regional Cancer Center
St. George, Utah, 84770, United States
Southwestern Vermont Medical Center
Bennington, Vermont, 05201, United States
Rutland Regional Medical Center
Rutland, Vermont, 05701, United States
Norris Cotton Cancer Center-North
Saint Johnsbury, Vermont, 05819, United States
Inova Alexandria Hospital
Alexandria, Virginia, 22304, United States
Danville Regional Medical Center
Danville, Virginia, 24541, United States
Augusta Health Cancer Center
Fishersville, Virginia, 22939, United States
Sentara Cancer Institute at Sentara CarePlex Hospital
Hampton, Virginia, 23666, United States
Sentara Rockingham Memorial Hospital Hahn Cancer Center
Harrisonburg, Virginia, 22801, United States
Sentara Hospitals
Norfolk, Virginia, 23507, United States
Southwest VA Regional Cancer Center
Norton, Virginia, 24273, United States
Naval Medical Center - Portsmouth
Portsmouth, Virginia, 23708-2197, United States
Oncology and Hematology Associates of Southwest Virginia
Roanoke, Virginia, 24014, United States
Sentara Virginia Beach General Hospital
Virginia Beach, Virginia, 23454, United States
PeaceHealth Saint Joseph Medical Center
Bellingham, Washington, 98225, United States
Saint Francis Hospital
Federal Way, Washington, 98003, United States
Virginia Mason CCOP
Seattle, Washington, 98101, United States
Virginia Mason Medical Center
Seattle, Washington, 98101, United States
Cancer Care Northwest - Spokane South
Spokane, Washington, 99202, United States
Cancer Care Northwest-North Spokane
Spokane, Washington, 99218, United States
PeaceHealth Southwest Medical Center
Vancouver, Washington, 98664, United States
Compass Oncology Vancouver
Vancouver, Washington, 98684, United States
Legacy Salmon Creek Hospital
Vancouver, Washington, 98686, United States
Appleton Medical Center
Appleton, Wisconsin, 54911, United States
Green Bay Oncology at Saint Vincent Hospital
Green Bay, Wisconsin, 54301-3526, United States
Bellin Memorial Hospital
Green Bay, Wisconsin, 54301, United States
Saint Vincent Hospital
Green Bay, Wisconsin, 54301, United States
Green Bay Oncology Limited at Saint Mary's Hospital
Green Bay, Wisconsin, 54303, United States
Saint Mary's Hospital
Green Bay, Wisconsin, 54303, United States
Aurora BayCare Medical Center
Green Bay, Wisconsin, 54311-6519, United States
UW Cancer Center Johnson Creek
Johnson Creek, Wisconsin, 53038, United States
Gundersen Lutheran Medical Center
La Crosse, Wisconsin, 54601, United States
Mayo Clinic Health System-Franciscan Healthcare
La Crosse, Wisconsin, 54601, United States
Bay Area Medical Center
Marinette, Wisconsin, 54143, United States
Vince Lombardi Cancer Clinic-Marinette
Marinette, Wisconsin, 54143, United States
Community Memorial Hospital
Menomonee Falls, Wisconsin, 53051, United States
Columbia Saint Mary's Hospital - Ozaukee
Mequon, Wisconsin, 53097, United States
Columbia Saint Mary's Water Tower Medical Commons
Milwaukee, Wisconsin, 53211, United States
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin, 53215, United States
Froedtert and the Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
Zablocki Veterans Administration Medical Center
Milwaukee, Wisconsin, 53295, United States
Green Bay Oncology - Oconto Falls
Oconto Falls, Wisconsin, 54154, United States
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin, 54904, United States
Wheaton Franciscan Cancer Care - All Saints
Racine, Wisconsin, 53405, United States
Door County Cancer Center
Sturgeon Bay, Wisconsin, 54235-1495, United States
Green Bay Oncology - Sturgeon Bay
Sturgeon Bay, Wisconsin, 54235, United States
Aurora Medical Center in Summit
Summit, Wisconsin, 53066, United States
Aurora West Allis Medical Center
West Allis, Wisconsin, 53227, United States
The Alyce and Elmore Kraemer Cancer Care Center
West Bend, Wisconsin, 53095, United States
Riverview Hospital
Wisconsin Rapids, Wisconsin, 54494, United States
Welch Cancer Center
Sheridan, Wyoming, 82801, United States
Tom Baker Cancer Centre
Calgary, Alberta, T2N 4N2, Canada
Cross Cancer Institute
Edmonton, Alberta, T6G 1Z2, Canada
BCCA-Cancer Centre for the Southern Interior
Kelowna, British Columbia, V1Y 5L3, Canada
BCCA-Vancouver Island Cancer Centre
Victoria, British Columbia, V8R 6V5, Canada
Atlantic Health Sciences Corporation-Saint John Regional Hospital
Saint John, New Brunswick, E2L 4L2, Canada
QEII Health Sciences Centre/Capital District Health Authority
Halifax, Nova Scotia, B3H 1V8, Canada
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, L8V 5C2, Canada
London Regional Cancer Program
London, Ontario, N6A 4L6, Canada
Ottawa Health Research Institute-General Division
Ottawa, Ontario, K1H 1C4, Canada
Irving Greenberg Family Cancer Centre
Ottawa, Ontario, K2H 8P4, Canada
Thunder Bay Regional Health Science Centre
Thunder Bay, Ontario, P7B 6V4, Canada
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N 3M5, Canada
Hopital Maisonneuve-Rosemont
Montreal, Quebec, H1T 2M4, Canada
CHUM - Hopital Notre-Dame
Montreal, Quebec, H2L 4M1, Canada
McGill University Department of Oncology
Montreal, Quebec, H2W 1S6, Canada
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ)
Québec, Quebec, G1R 2J6, Canada
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont
Sherbrooke, Quebec, J1H 5N4, Canada
Allan Blair Cancer Centre
Regina, Saskatchewan, S4T 7T1, Canada
Saskatoon Cancer Centre
Saskatoon, Saskatchewan, S7N 4H4, Canada
Related Publications (1)
Krauss DJ, Karrison T, Martinez AA, Morton G, Yan D, Bruner DW, Movsas B, Elshaikh M, Citrin D, Hershatter B, Michalski JM, Efstathiou JA, Currey A, Kavadi VS, Cury FL, Lock M, Raben A, Seaward SA, El-Gayed A, Rodgers JP, Sandler HM. Dose-Escalated Radiotherapy Alone or in Combination With Short-Term Androgen Deprivation for Intermediate-Risk Prostate Cancer: Results of a Phase III Multi-Institutional Trial. J Clin Oncol. 2023 Jun 10;41(17):3203-3216. doi: 10.1200/JCO.22.02390. Epub 2023 Apr 27.
PMID: 37104748DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Results Point of Contact
- Title
- Wendy Seiferheld
- Organization
- NRG Oncology
Study Officials
- STUDY CHAIR
Alvaro A. Martinez, MD, FACR
21st Century Oncology - Michigan Institute for Radiation Oncology
Publication Agreements
- PI is Sponsor Employee
- No
- Restriction Type
- OTHER
- Restrictive Agreement
- Yes
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- NETWORK
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 8, 2009
First Posted
July 10, 2009
Study Start
September 1, 2009
Primary Completion
October 3, 2020
Study Completion
September 4, 2025
Last Updated
March 6, 2026
Results First Posted
October 6, 2022
Record last verified: 2025-09