NCT00934622

Brief Summary

This study will involve up to 20 bilateral patients per surgeon. Patients will be assessed pre-operatively, and at subsequent visits (following the implantation of the intraocular lens in the second eye) at 1 week, 1 month, 3 months and 6 months post-operatively.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
76

participants targeted

Target at P25-P50 for phase_4

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2007

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2009

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

July 7, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

July 8, 2009

Completed
10 months until next milestone

Results Posted

Study results publicly available

May 6, 2010

Completed
Last Updated

May 6, 2010

Status Verified

May 1, 2010

Enrollment Period

1.3 years

First QC Date

July 7, 2009

Results QC Date

March 25, 2010

Last Update Submit

May 5, 2010

Conditions

Keywords

AcrySofReSTORAspheric IOLCataract

Outcome Measures

Primary Outcomes (1)

  • Visual Acuity

    Comparison of visual acuity (measured in logMAR) prior to and following bilateral implantation of the AcrySof ReSTOR Aspheric Intraocular Lens (IOL). Visual parameters were assessed prior to and after the implantation of the second lens at 1 week, 1 month, 3 months, and 6 months. LogMAR, the unit of measure for visual acuity, is the "logarithm of the minimum angle of resolution". A lower logMAR value indicates better visual acuity.

    pre-operative;1 week,1 month, 3 months and 6 months after 2nd eye surgery

Secondary Outcomes (1)

  • Spectacle Independence

    pre-op;1 week,1 month,3 months and 6 months after 2nd eye surgery

Study Arms (1)

AcrySof® ReSTOR® Aspheric IOL

EXPERIMENTAL

AcrySof® ReSTOR® Aspheric Intraocular Lens (IOL)

Device: AcrySof® ReSTOR® Aspheric IOL

Interventions

AcrySof® ReSTOR® Aspheric Intraocular Lens (IOL) implanted into the study eye following the cataract extraction surgery

AcrySof® ReSTOR® Aspheric IOL

Eligibility Criteria

Age21 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years or older;
  • need spherical correction between 10-30 Diopters (D);
  • corneal astigmatism less than 0.75D as measured by keratometry;
  • willing to sign an Informed Consent Form and complete all visits;
  • pupil dilation greater than 6mm;
  • expected Visual Acuity (measured in logMAR)=0.3 or better

You may not qualify if:

  • Women of childbearing potential;
  • irregular corneal astigmatism;
  • keratopathy/keratectasia;
  • cornea inflammation or edema;
  • cornea reshaping surgery;
  • corneal dystrophy;corneal transplant;
  • amblyopia;
  • glaucoma;
  • Retinal Pigment Epitheliopathy (RPE)/Macular changes;
  • proliferative diabetic retinopathy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Alcon Call Center for Trial Locations

Fort Worth, Texas, 76134, United States

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Results Point of Contact

Title
Alcon Clinical
Organization
Alcon Research, Ltd.

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
LTE60
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

July 7, 2009

First Posted

July 8, 2009

Study Start

November 1, 2007

Primary Completion

March 1, 2009

Last Updated

May 6, 2010

Results First Posted

May 6, 2010

Record last verified: 2010-05

Locations