NCT00933192

Brief Summary

The evaluation of skeletal muscle strength in severly ill or cognitive impaired patients is an unresolved problem especially during the rehabilitation process. The aim of this study is to correlate morphological parameters assessed with muscle ultrasound and isometric muscle strength to establish an objective progression parameter for rehabilitation therapies.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2009

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2009

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

July 2, 2009

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 7, 2009

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2010

Completed
Last Updated

April 16, 2010

Status Verified

April 1, 2010

Enrollment Period

8 months

First QC Date

July 2, 2009

Last Update Submit

April 15, 2010

Conditions

Skeletal Muscle UltrasoundIsometric Muscle Strength

Study Arms (2)

Group 1: young healthy patients

Device: Siemens Acuson Antares ultrasound

Group 2: old healthy patients

Device: Siemens Acuson Antares ultrasound

Interventions

Siemens Acuson Antares ultrasoundDEVICE

skeletal muscle ultrasound of the musculus quadriceps, on two different days, two observers

Group 1: young healthy patientsGroup 2: old healthy patients

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

outpatients or inpatients of the institute of physical medicine and rehabilitaion

You may qualify if:

  • group 1: patients between 18 and 35 years
  • group 2: patients between 60 and 80 years

You may not qualify if:

  • neuromuscular diseases
  • hip or knee prosthesis in the investigated leg
  • any trauma of the hip, knee or ankle of the investigated leg during the last 12 months
  • cognitive impairments
  • pregnancy
  • diabetes mellitus Type II
  • acute or chronic pain in the investigated leg
  • chronic maligne or non - maligne diseases (of the heart, lung or kidney)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Karl Landsteiner Institute of Remobilisation and Functional Health

Vienna, Vienna, 1100, Austria

Location

Related Publications (1)

  • Strasser EM, Draskovits T, Praschak M, Quittan M, Graf A. Association between ultrasound measurements of muscle thickness, pennation angle, echogenicity and skeletal muscle strength in the elderly. Age (Dordr). 2013 Dec;35(6):2377-88. doi: 10.1007/s11357-013-9517-z. Epub 2013 Mar 2.

    PMID: 23456136DERIVED

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

July 2, 2009

First Posted

July 7, 2009

Study Start

July 1, 2009

Primary Completion

March 1, 2010

Study Completion

March 1, 2010

Last Updated

April 16, 2010

Record last verified: 2010-04

Locations

AU(1)