Stent Thrombosis In Acute Coronary Syndromes

NCT00931502 | Completed

• 2 other identifiers: 214693STR 001
• Study Type: observational
• Target: 800
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to better understand what treatment methods result in the best outcomes for patients who have heart attacks due to blood clots forming within stents.

Conditions

Stent Thrombosis; Acute Coronary Syndrome

Keywords

Stent thrombosis; Acute Coronary Syndrome; ACS; Stenting; Interventional Cardiology; Cardiology; Cardiovascular Research; Registry

Outcome Measures

Primary Outcomes (1)

• To describe current real world practice in the treatment of ACS due to stent thrombosis.

  3 years

Secondary Outcomes (1)

• To describe early and long term follow up of patients who are treated for ACS due to stent thrombosis.

  3 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who have had a heart attack or almost have had a heart attack due to blood clots forming within previously placed stents.

You may qualify if:

• Subject's age range will be ≥ 18 years old.
• Subjects will have an existing drug-eluting or bare metal stent.
• Subjects will have presented to the Medical Center with Acute Coronary Syndrome due to stent thrombosis as identified via cardiac catheterization.

You may not qualify if:

• Inability to consent/declined to participate in the prospective arm of the clinical registry.

Sponsors & Collaborators

• University of California, Davis: lead
• University of California, San Diego: collaborator

Study Sites (1)

UC Davis Medical Center

Sacramento, California, 95817, United States

Location

Related Publications (3)

• Reeves RR, Patel M, Armstrong EJ, Sab S, Waldo SW, Yeo KK, Shunk KA, Low RI, Rogers JH, Mahmud E. Angiographic characteristics of definite stent thrombosis: role of thrombus grade, collaterals, epicardial coronary flow, and myocardial perfusion. Catheter Cardiovasc Interv. 2015 Jan 1;85(1):13-22. doi: 10.1002/ccd.25519. Epub 2014 May 7.

  PMID: 24753053 DERIVED

• Waldo SW, Armstrong EJ, Yeo KK, Patel M, Reeves R, Macgregor JS, Low RI, Mahmud E, Rogers JH, Shunk K. Procedural success and long-term outcomes of aspiration thrombectomy for the treatment of stent thrombosis. Catheter Cardiovasc Interv. 2013 Dec 1;82(7):1048-53. doi: 10.1002/ccd.25007. Epub 2013 Jul 2.

  PMID: 23703925 DERIVED

• Armstrong EJ, Yeo KK, Javed U, Mahmud E, Patel M, Shunk KA, MacGregor JS, Low RI, Rogers JH. Angiographic stent thrombosis at coronary bifurcations: short- and long-term prognosis. JACC Cardiovasc Interv. 2012 Jan;5(1):57-63. doi: 10.1016/j.jcin.2011.09.015.

  PMID: 22230151 DERIVED

MeSH Terms

Conditions

Acute Coronary Syndrome

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases

Study Officials

• Jason Rogers, MD

  University of California, Davis

  PRINCIPAL INVESTIGATOR

• Khung Keong Yeo, MD

  University of California, Davis

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 29, 2009
• First Posted: July 2, 2009
• Study Start: April 1, 2008
• Primary Completion: February 1, 2017
• Study Completion: February 1, 2017
• Last Updated: March 2, 2018

Record last verified: 2018-03

Locations

US (1)