NCT00927108

Brief Summary

To study the success of Oligodendrocyte progenitor cell culture project in Rajavithi Hospital to identify an unlimited clone human neuronal progenitor stem cells from the human brain in the Biomolecular Research Center. This study aims to produce the reproductive clone of neuronal development protocols and advance projects. Neuronal cells such as pyramidal cells, oligodendrocyte, and dopaminergic neuron differentiation protocol/projects for treatment of Alzheimer's disease, Multiple sclerosis, and Parkinson's disease respectively in next phase of clinical trials.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Jul 2009

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 22, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 24, 2009

Completed
7 days until next milestone

Study Start

First participant enrolled

July 1, 2009

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2011

Completed
Last Updated

October 19, 2020

Status Verified

October 1, 2020

Enrollment Period

2.4 years

First QC Date

June 22, 2009

Last Update Submit

October 14, 2020

Conditions

Alzheimer's DiseaseParkinson's DiseaseMultiple Sclerosis

Keywords

Adult Progenitor Stem cellsAlzheimer's diseaseParkinson's diseaseMultiple sclerosis

Interventions

Progenitor Stem Cell CultureOTHER

Eligibility Criteria

Age20 Years - 120 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients who have elective craniotomy or.
  • Patients who have elective ventriculostomy surgery or.
  • Patients who have elective muscle biopsy or nerve biopsy.
  • Patient who have emergency craniectomy for life threatening from emergency medical and surgical conditions such as Brain herniation or head injury

You may not qualify if:

  • Central nervous system infection for example tuberculous or any bacterial infection, Viral infection, fungal infection.
  • Central nervous system Tumor, Malignancy and metastasis.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Rajavithi Hospital

Bangkok, 10140, Thailand

Location

MeSH Terms

Conditions

Alzheimer DiseaseParkinson DiseaseMultiple Sclerosis

Condition Hierarchy (Ancestors)

DementiaBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesTauopathiesNeurodegenerative DiseasesNeurocognitive DisordersMental DisordersParkinsonian DisordersBasal Ganglia DiseasesMovement DisordersSynucleinopathiesDemyelinating Autoimmune Diseases, CNSAutoimmune Diseases of the Nervous SystemDemyelinating DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Subsai Kongsaengdao, M.D.

    Department of Medical Services Ministry of Public Health of Thailand

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
phase 2
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Model Details: Cell culture
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 22, 2009

First Posted

June 24, 2009

Study Start

July 1, 2009

Primary Completion

December 1, 2011

Study Completion

December 1, 2011

Last Updated

October 19, 2020

Record last verified: 2020-10

Locations

TH(1)