Study Stopped
When 9 subjects of targeted 12 subjects had been studied, no changes in plasma potassium were detected and it was deemed futile to continue with enrolment.
The Effect of Liquorice on Plasma Potassium
Lakritsin Vaikutus Kaliumpitoisuuteen
1 other identifier
interventional
9
1 country
1
Brief Summary
The hypothesis is that liquorice lowers plasma potassium. This study aims to elucidate the dose-response of this effect with two doses of liquorice (66 grams or 102 grams) per day for two weeks.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable healthy
Started Jun 2009
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2009
CompletedFirst Submitted
Initial submission to the registry
June 22, 2009
CompletedFirst Posted
Study publicly available on registry
June 24, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2010
CompletedApril 7, 2010
April 1, 2010
9 months
June 22, 2009
April 6, 2010
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Change in plasma potassium
1 week, 2 weeks
Study Arms (2)
Liquorice 66 g/day
ACTIVE COMPARATORLiquorice given 66 grams per day for two weeks
Liquorice 102 g/day
ACTIVE COMPARATORLiquorice given 102 grams per day for two weeks
Interventions
Liquorice 66 g/day for two weeks
Liquorice 102 g/day for two weeks
Eligibility Criteria
You may qualify if:
- healthy volunteers
- age 18-40
You may not qualify if:
- any continuous medication
- hypertension or hypotension
- allergy to liquorice
- pregnancy or lactation
- difficult venipuncture
- drug or alcohol abuse
- participation in pharmaceutical trial
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Oulu University Hospital
Oulu, 90220, Finland
MeSH Terms
Interventions
Study Officials
- PRINCIPAL INVESTIGATOR
Janne Hukkanen, MD, PhD
Oulu University Hospital, Department of Internal Medicine
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
June 22, 2009
First Posted
June 24, 2009
Study Start
June 1, 2009
Primary Completion
March 1, 2010
Study Completion
March 1, 2010
Last Updated
April 7, 2010
Record last verified: 2010-04