NCT00925379

Brief Summary

Evaluation of the frequency of familial cases of renal HYPODYSPLASIA

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
342

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2009

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2009

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

June 19, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 22, 2009

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2013

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2014

Completed
Last Updated

November 20, 2025

Status Verified

September 1, 2025

Enrollment Period

4 years

First QC Date

June 19, 2009

Last Update Submit

November 17, 2025

Conditions

Renal HYPODYSPLASIA, Nonsyndromic, 1

Outcome Measures

Primary Outcomes (1)

  • Evaluation of the heritability of renal HYPODYSPLASIA (on the renal ultra sound) and DNA collection to make possible identification of predisposing genes

    the same day

Eligibility Criteria

Age3 Months - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Children with a bilateral renal hypodysplasia

You may qualify if:

  • \- Children aged more than 3 months and less than 18 years old with a renal bilateral HYPODYSPLASIA set by renal ultrasound examination :
  • renal size \< -2DS
  • with/or hyperechogenicity or lack of cortical-medullary differentiation
  • with/or renal cysts

You may not qualify if:

  • Bladder uropathy or sus-bladder uropathy
  • Recessive or dominant renal polycystic disease
  • Bardet-Biedl syndrome and other malformative syndromes except renal coloboma syndrome, Renal cysts and diabetes syndrome RCAD
  • Lack of written informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Necker Hospital

Paris, 75015, France

Location

Biospecimen

Retention: SAMPLES WITH DNA

DNA collection from the propositus and its parents and in case of families with more than one affected member, collection of DNA from the all family.

MeSH Terms

Conditions

Renal Hypodysplasia, Nonsyndromic, 1

Study Officials

  • Remi Salomon, MD, PhD

    Assistance Publique - Hôpitaux de Paris

    PRINCIPAL INVESTIGATOR

  • Vincent Guigonis, MD, PhD

    University Hospital, Limoges

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 19, 2009

First Posted

June 22, 2009

Study Start

April 1, 2009

Primary Completion

April 1, 2013

Study Completion

July 1, 2014

Last Updated

November 20, 2025

Record last verified: 2025-09

Locations

FR(1)