The Early Origins of Cardiovascular Disease
1 other identifier
observational
200
1 country
1
Brief Summary
Small body size at birth, slow weight gain during infancy and increase in body mass index after 2 years are independent risk factors for cardiovascular disease and the metabolic syndrome. There is a large gap in our understanding of how early growth affects the cardiovascular system. Possible mechanisms include alterations in body composition, in cardiac structure, in vascular function, in renal function and epigenetic processes. The Objective is to determine how size at birth and growth during infancy and childhood affect: body composition, cardiac structure and function, vascular and endothelial function, renal function, metabolic status and transcriptional and epigenetic characteristics.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
1 active site
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Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2009
CompletedFirst Submitted
Initial submission to the registry
June 17, 2009
CompletedFirst Posted
Study publicly available on registry
June 18, 2009
CompletedJune 18, 2009
June 1, 2009
June 17, 2009
June 17, 2009
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
To determine how size at birth and growth during infancy and childhood affect: body composition, cardiac structure and function, vascular and endothelial function, renal function, metabolic status and transcriptional and epigenetic characteristics
3 years
Study Arms (1)
Exposed/ Not exposed
Eligibility Criteria
200 Young adult students will be recruited at the Preventive Medicine Centre at Université de la Méditerranée during their annual routine medical examination
You may qualify if:
- Male and female volunteers students aged between 18-25 years old
- Having growth records
You may not qualify if:
- If young women subject without contraception,or pregnant
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
CIC-UPCET Hopital de la Timone Bat F
Marseille, 13385, France
MeSH Terms
Conditions
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
June 17, 2009
First Posted
June 18, 2009
Study Start
June 1, 2009
Last Updated
June 18, 2009
Record last verified: 2009-06