NCT00920777

Brief Summary

The purpose of this study is to analyze income variables in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis, and to analyze the effect of short vs. long Cognitive Behaviour Therapy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
234

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2009

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2009

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

June 12, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 15, 2009

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2014

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2015

Completed
Last Updated

June 9, 2020

Status Verified

June 1, 2020

Enrollment Period

5.2 years

First QC Date

June 12, 2009

Last Update Submit

June 6, 2020

Conditions

Keywords

CBTFukuda criteriaMental functioningPhysical functioning

Outcome Measures

Primary Outcomes (1)

  • Mental and physical function

    Mental and physical function, measured by "SF 36". Success criteria are measured by \>10 point improvement of mental and/ or physical function.

    1 year

Study Arms (3)

8 weeks CBT

EXPERIMENTAL
Behavioral: CBT

Control group

ACTIVE COMPARATOR
Behavioral: Control group

16 weeks CBT

EXPERIMENTAL
Behavioral: CBT

Interventions

CBTBEHAVIORAL

Individual Cognitive Behavior Therapy during 16 weeks

Also known as: Grades excercise therapy
16 weeks CBT
Control groupBEHAVIORAL

Waiting 16 weeks and receiving 8 weeks individual CBT after waiting period.

Control group

Eligibility Criteria

Age18 Years - 62 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients referred to St.Olav Hospital, Trondheim
  • fulfil the FUKUDA criteria for CFS/ME.

You may not qualify if:

  • Pregnant patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

St.Olavs Hospital

Trondheim, 7006, Norway

Location

Related Publications (2)

  • Rasouli O, Gotaas ME, Stensdotter AK, Skovlund E, Landro NI, Dastol P, Fors EA. Neuropsychological dysfunction in chronic fatigue syndrome and the relation between objective and subjective findings. Neuropsychology. 2019 Jul;33(5):658-669. doi: 10.1037/neu0000550. Epub 2019 Jun 6.

  • Gotaas ME, Stiles TC, Bjorngaard JH, Borchgrevink PC, Fors EA. Cognitive Behavioral Therapy Improves Physical Function and Fatigue in Mild and Moderate Chronic Fatigue Syndrome: A Consecutive Randomized Controlled Trial of Standard and Short Interventions. Front Psychiatry. 2021 Apr 12;12:580924. doi: 10.3389/fpsyt.2021.580924. eCollection 2021.

MeSH Terms

Conditions

Fatigue Syndrome, ChronicFatiguePain

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesEncephalomyelitisNeuroinflammatory DiseasesNervous System DiseasesNeuromuscular DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsSigns and SymptomsNeurologic Manifestations

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Study Officials

  • Egil Fors, prof MD

    St. Olavs Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 12, 2009

First Posted

June 15, 2009

Study Start

May 1, 2009

Primary Completion

July 1, 2014

Study Completion

May 1, 2015

Last Updated

June 9, 2020

Record last verified: 2020-06

Locations